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Large GBR long distance triathlete. Critical Care @BTHFT, head of Clinical AI, fellow @AAIP_York & Hon. Prof. MBE. Ran in a mask once. (he) @LawtonTri@mas.to
Dame ChrisπŸŒŸπŸ‡ΊπŸ‡¦πŸ˜· #RejoinEU #FBPE #GTTOπŸ”ΆοΈ Profile picture 1 subscribed
Jul 13, 2023 β€’ 5 tweets β€’ 2 min read
Hospital-Acquired Covid in England - 13th July 2023

Today was the first release of the NHS Monthly data since the weekly data was reduced to the point that it was no longer possible to report on hospital-acquired Covid. I promised an update so here it is...

1/ Unfortunately, the monthly data has also been reduced and now only reports whether people were diagnosed on or after coming to hospital. Those diagnosed after admission will include people catching it in hospital, but also some who caught it earlier.

2/
Jun 8, 2023 β€’ 9 tweets β€’ 3 min read
Hospital-acquired Covid-19 in England

In the last 365 days, of 290,121 patients in hospital with Covid-19, 83,355 probably or definitely caught it there (28.7%)

There isn't a data release today; possibly there won't be a suitable one again. So here's a summary.

1/ HAI percentage - stubbornly... Over 83,000 people with hospital-acquired Covid-19 in a year (and likely an underestimate!). Many of these will have died.

For reference, c.diff reports are about 5,000 a year. MRSA bacteraemia about 1,000. These are infections that we (rightly) are working hard to prevent.

2/ MRSA bacteraemia - hospital...
Jun 1, 2023 β€’ 5 tweets β€’ 2 min read
Hospital-Acquired COVID-19 in England, 1st June 2023

In the last 28 days, of 10,472 patients in hospital with Covid-19, 3,174 probably or definitely caught it there (30.3%)

All the data were still released today; it may be that *after* today it goes - but let's see.

1/ Overall percentage - back o... Absolute values still show a downward trend (and yes I think this is real), but the rising percentage suggests that this is just because of low prevalence rather than that we've fundamentally improved things.

2/ Absolute values - still fal...
May 25, 2023 β€’ 5 tweets β€’ 2 min read
Hospital-Acquired COVID-19 in England, 25th May 2023

In the last 28 days, of 11,734 patients in hospital with Covid-19, 3,488 probably or definitely caught it there (29.7%)

This *may* be the last update - a lot of data is going away on 1st June; I will see what remains.

1/ Overall percentage - starti... At least we may be ending on a low for absolute values; though at just below 30% the percentage remains concerningly high (and rising).

2/ Absolute values - still dro...
Apr 13, 2023 β€’ 7 tweets β€’ 3 min read
Hospital-Acquired COVID-19 in England, 13th Apr 2023

In the last 28 days, of 24,761 patients in hospital with Covid-19, 7,354 probably or definitely caught it there (29.7%)

Finally below 30% - but we still have some way to go!

1/ Overall percentage - finall... Absolute numbers suggest that this latest wave might be coming to an end. But the rising baseline still looks very concerning - what are we doing to try to reduce this?

2/ Absolute numbers. Latest wa...
Mar 16, 2023 β€’ 5 tweets β€’ 2 min read
Hospital-Acquired COVID-19 in England, 16th Mar 2023

In the last 28 days, of 26,484 patients in hospital with Covid-19, 8,644 probably or definitely caught it there (32.6%)

Looks like >30% is standard now. This isn't great.

1/ Time series of hospital acquired Covid percentage. Steady at On the chart of absolute numbers, it becomes clear that last week's "long peak" wasn't even that - it's going back up.

2/ Absolute numbers of hospital-acquired Covid in each wave. La
Dec 22, 2022 β€’ 6 tweets β€’ 3 min read
Hospital-acquired COVID-19 in England, 22nd December 2022

In the last 28 days, of 20,706 patients in hospital with Covid-19, 7,467 probably or definitely caught it there (36.1%)

I'm running out of things to say if I'm honest. This needs fixing.

1/ Time series of percentage hospital-acquired infections. Risi The fifth hospital-acquired wave is well under way. If it's like the others (including the 2020/21 wave) it will peak at around 10,000 patients per month being infected in English hospitals.

2/ Time series of cases. Picking back up above 5,000 this wave
Dec 8, 2022 β€’ 6 tweets β€’ 2 min read
Hospital-acquired COVID-19 in England, 8th December 2022

In the last 28 days, of 15,121 patients in hospital with Covid-19, 4,680 probably or definitely caught it there (31.0%)

This is definitely getting worse again.

1/ Time series of hospital-acquired COVID-19. Over 30% again. Estimated 7-day risk (for those who came in without it) by trust varies massively. Unfortunately, hospitals are full and cohorting is difficult. Could attention to air quality help even if we might struggle with the rest given current resourcing?

2/ Estiumated 7-day risk - varies from 0% to 3.5%
Oct 6, 2022 β€’ 5 tweets β€’ 2 min read
Hospital-Acquired COVID-19 - 6th Oct update

I have to admit to being surprised at how high the numbers are getting. In the last 28 days, out of 21,809 people admitted to hospital with Covid in England, 7,908 probably or definitely caught it there (36.3%)

1/ Percentage hospital-acquire... Some of this will be testing behaviours, but we're seeing more and more evidence that the proportion of people coming to hospital with something else and catching Covid there is higher than it should be, and growing. And Covid is unlikely to help make them better.

2/ Chart of estimated 7-day ri...
Jan 28, 2022 β€’ 11 tweets β€’ 6 min read
In case you've missed it, a UK study is planned comparing filtering masks with non-filtering ones to prevent respiratory infections in healthcare workers.

People have compared the ethics of this to steel-capped boots vs slippers on a building site, but I have other concerns.

1/ WIPPET: The impact of diffe... This study was designed at a time when UK guidance allowed surgical masks for an airborne disease (so long as it wasn't "wholly" airborne). In fact, I'm told some of the study team were involved in creation of this guidance!

The study then tests an "upgrade" to real PPE.

2/
Nov 18, 2021 β€’ 6 tweets β€’ 2 min read
In conversation with @microlabdoc earlier, I discovered that not everyone knows of the hamster's prodigious capacity for alcohol.

They love it so much they prefer to drink 15% ethanol instead of water, and can tolerate relative quantities that would kill a human. 1/ Given the choice, they will consume up to 20g/kg ethanol a day - equivalent to a "standard man" drinking 21 bottles of wine each day.

They are so keen on the stuff that real research has been done into getting hamsters off the sauce (I'm not sure if Ig Nobel got involved). 2/
Oct 26, 2021 β€’ 9 tweets β€’ 10 min read
@CathNoakes @mjb302 @LadyScorcher @hughes_eilir I think that's one of the reasons we get so excitable about this. I vividly remember planning with colleagues for a virus we thought we'd probably catch, with - at the time - a high fatality rate.

It sounds silly now, but we definitely thought one of us would probably die. 1/ @CathNoakes @mjb302 @LadyScorcher @hughes_eilir And the fact is that, whilst my immediate colleagues and I were safe in our (airborne) PPE, and the death rate was much lower than those early estimates, hundreds of NHS staff have died - and a lot of those infections will have been caught in the workplace. 2/
Sep 24, 2021 β€’ 11 tweets β€’ 5 min read
Our new preprint on hospital-acquired COVID-19 in NHS Trusts in England

Based on the analyses we've been doing of HAIs in England.

First the good news: rates have dropped, from 14.3% to 4.2% over the last 12 months

1/

authorea.com/doi/full/10.22… ImageImage Why? Not clear but I think most would agree a focus on regular testing and cohorting patients, and good basic infection control practices have helped.

We've also started to accept that #COVIDIsAirborne - but its implications aren't fully embedded in the NHS.

2/
Aug 6, 2021 β€’ 25 tweets β€’ 8 min read
COVID-19 and CPAP - a thread attempting to explain to non-medics
After a request from @fascinatorfun

Please excuse the fact I will inevitably fail and use jargon; I've been living this for 18 months now and I'm not sure my brain works good any more. Please ask questions! 1/ A main reason someone with COVID-19 may end up in hospital is breathing. It attacks the lungs in a way that makes it hard for oxygen to get into the blood leading to "hypoxia" (low oxygen levels). As our breathing is mostly based on CO2 the patient may initially feel OK. 2/
Aug 5, 2021 β€’ 9 tweets β€’ 3 min read
RECOVERY-RS results out, and confirm what most of us have been doing:

CPAP reduces intubation/mortality by 28% compared with no CPAP/HFNO (composite outcome, mostly intubation)
Nasal high flow not so successful

1/

medrxiv.org/content/10.110… Interestingly, CPAP reduced the duration of invasive ventilation even in those who were intubated - so possible that delaying intubation is no bad thing.

Estimate of 15% mortality reduction, but underpowered (I do wonder how many patients were eligible but not recruited)

2/
Jun 28, 2021 β€’ 6 tweets β€’ 3 min read
At #FreshAirNHS we've pushed for airborne precautions for an airborne disease for a while, but the UK guidance has lagged behind - and now suggests NHS trusts must make their own decision.

@CUH_NHS decided to use FFP3 respirators for COVID-19 care, and now provide data. 1/ A simple swap of surgical masks (droplet) for FFP3 (airborne) appears to have eliminated the excess risk of infection from working on a red ward - from what was a 47-fold increase. 2/
Jun 3, 2021 β€’ 12 tweets β€’ 3 min read
As a researcher working with data like this, I'm aware there is a balance between the needs to plan and research, and to reassure people about what happens to their data - particularly health data which was given in the expectation of confidentiality. 1/

theguardian.com/commentisfree/… There has been a growth - particularly during the pandemic - of massive databases seeking to include as much of the UK population as they can. And COPI rules have (temporarily) removed many of the protections people believed they had. 2/
Jan 30, 2021 β€’ 7 tweets β€’ 3 min read
Updated chart of probable hospital-acquired COVID-19
(diagnosed over 7 days after hospital admission)

English Acute Trusts with over 300 total cases since August 2020

Can we share learning points from the Trusts near the bottom? Image Updated chart (data to 31st Jan 21)

Probable hospital acquired COVID-19 (diagnosed >7 days after admission).
English Acute Trusts with over 300 cases since August 2020

Chart shows percentage of cases that are probable HAI, and total case numbers. Image
Jan 11, 2021 β€’ 10 tweets β€’ 3 min read
A quick thread on running in masks

I should start by saying I'm not advocating for masks outside; but like all good scientists I reserve the right to change my opinion.

However there are rumours UK rules may change, and I've done this before...

1/

yorkshireeveningpost.co.uk/health/coronav… So after being tagged in some discussions I ran home today testing three different masks to remind myself of my original run (which was in a "nan's curtains" 3-layer cloth mask)

But first a few tips on masked running:

2/
May 4, 2020 β€’ 19 tweets β€’ 3 min read
There is an urban myth in anaesthesia about August Bier, his assistant Hildebrandt, and the invention of spinal anaesthesia. We were having a giggle about it on Covid ICU this weekend – but it turns out the truth is so much better:

(a thread, edited from the paper) (1/n) At 7:38 p.m. I injected 0.5 cc. of a 1 per cent solution of cocaine. This resulted in Hildebrandt experiencing a feeling of warmth in both legs.

After 7 minutes: Needle pricks in the thigh were perceived as pressure; tickling of the the sole of the foot was barely felt. (2/n)