🩻PET/CT: 3.5 cm mass LLL & bulky, coalescing LNs in L hilum & mediastinum (AP 🪟, subcarinal, bilat paratracheal, supraclav)
Axillary LNs
🦴multi bony mets
🫀small pericardial effusion
@TumorBoardTues 2/17 #TumorBoardTuesday#LungCancer#NSCLC
🫁🎥Mediastinoscopy shows adenocarcinoma with signet rings.
🔬 ALK IHC positive
🐟 FISH positive
🧬 PDL1 = 0
🤨What’s your recommended initial therapy:
Jun 7, 2020 • 10 tweets • 21 min read
@LauraJBook Thanks for your help @LauraJBook. This is a commentary on the article by @AdamJSchoenfeld by my colleague @ZPiotrowskaMD. I think pts can’t see the full articles & are misinterpreting the abstract. Let me see if I can shed some light on this 1/n@LauraJBook@AdamJSchoenfeld@ZPiotrowskaMD To start with, SCLC transformation is still poorly understood. So we don’t have all the answers yet. From some brilliant work from @jakelee0711 we suspect that certain EGFR pts are predisposed to have this transformation and for others, it will not ever happen 2/n
