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Leonard Chiu, MD MS Profile picture
Leonard Chiu, MD MS
@LeonardChiuMD
Cardiology Fellow @UTSWCardFellow | formerly @VUMCMedicineRes @ColumbiaMed @Penn | Learning HF & CV Outcomes | @Raptors fan & 🎾 player
Jul 30, 2023 • 27 tweets • 7 min read
Hypertrophic cardiomyopathy is one of the most common causes of Sudden Cardiac Arrest in young adults. What is #HCM exactly?

A 🧵 on Hypertrophic Cardiomyopathy...1/24

We'll cover:
1) Dx criteria
2) Pathophys
3) Prevalence
4) Natural hx & Clinical clues
5) Management & NEW Tx Image First, what is #HCM?

Clinically diagnosed: unexplained LVH
➡️ Not accounted by pressure overload: HTN, aortic stenosis
➡️ Not accounted by infiltration: amyloid or Fabry’s

By ECHO in adults:
➡️ Ventricular wall ≥15 mm in absence of other dx
➡️ Family hx of HCM: wall ≥13 mm
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Oct 27, 2022 • 26 tweets • 14 min read
A 75 M with lumbar spinal stenosis, paroxysmal afib, presents with progressive SOB and a torn bicep. What is this physical exam finding called?

A #Tweetorial on Cardiac Amyloidosis...1/24

We'll cover:
1) Pathophys
2) Prevalence
3) Exam clues
4) Dx Algorithm
5) Mgt/Tx Image First, let's review the 2 types of Cardiac Amyloidosis

A) AL Amyloidosis
- Plasma cells overproduce light chains
- Misfolded light chains deposit in the heart

B) ATTR Amyloidosis
- Transthyretin is a tetramer that dissociates
- Misfolded aggregates deposit in the heart

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