Cell biologist studying how a heart grows and dies; also Blebbisomes. Associate Professor at Vanderbilt. Married to @gillianhoo.
Feb 1, 2021 • 13 tweets • 5 min read
Sarcomeres in cardiac myocytes (heart muscle cells) are mechanically coupled to focal adhesions through dorsal stress fiber-like structures. #cardiotwitter#CellBiology
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A thread based on Figure 1 of... molbiolcell.org/doi/10.1091/mb…
A mature adult cardiac myocyte is packed with sarcomeres, whose contractile forces are coupled to the extracellular environment. With sarcomeres so close to the plasma membrane, how can we study the nature of this coupling?
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