Neuroscience researcher @MGHMartinos / @HarvardMed and @PolyBioRF, researching #MEcfs, #LongCOVID, & #PTSD. (all opinions are my own)
Oct 21, 2023 • 9 tweets • 3 min read
New preprint of a #longCOVID study from us:
"Neuroinflammation in post-acute sequelae of COVID-19 (PASC) as assessed by [11C]PBR28 PET correlates with vascular disease measures"biorxiv.org/content/10.110…
We conducted PET neuroimaging on 12 long COVID patients with diverse symptoms, and compared to 43 healthy controls that had already been scanned in the same scanner under the same protocol (most pre-pandemic). The PET radioligand that we used detects the TSPO protein, and...
Dec 22, 2021 • 6 tweets • 2 min read
Important preprint just out from a large NIH and U-Maryland based team. The title make the point clearly: "SARS-CoV-2 Infection and Persistence Throughout the Human Body and Brain." researchsquare.com/article/rs-113…
As would be expected, this includes mild and even asymptomatic cases.
Many preprints that reported persistence and/or neuroinvasion were whittled down before final publication, so it's worth watching what happens here. And to be clear I'm saying that this paper will face a hostile review process, not that it was poorly done.
Aug 18, 2018 • 7 tweets • 5 min read
@adambeyoncelowe@MECFSNews Brainstem is where people should be looking IMO. I suspect there will have a be a sort of panel of scan sequences in order to have any kind of discriminant validity that can meaningfully distinguish this condition from other conditions. ....
@adambeyoncelowe@MECFSNews Given that they did not perform a brainstem-specific structural registration, we can't make *too* much out of it, but take a look at how their finding lines up with the dorsal vagal complex (NTS/DMV)
