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Mike Fainzilber Profile picture
Mike Fainzilber
@MFainzilber
Molecular neuroscience, cell biology, aikido and haiku, not necessarily in that order. Find me at @mfainzilber@fediscience.org if and when this place goes under
Jul 31, 2023 • 14 tweets • 3 min read
PTBP1 regulates injury responses and sensory pathways in adult peripheral neurons | Science Advances

Our just-published paper includes the following timeline:
Submitted 29 March 2023
Accepted 22 June 2023
Published 28 July 2023

Not quite... 🧵science.org/doi/10.1126/sc… Our 1'st submission was in October 2020. At that time we also posted a preprint to @bioRxiv, see biorxiv.org/content/10.110…
Sep 30, 2021 • 6 tweets • 2 min read
"Knockdown of PTBP1 FAILS TO CONVERT brain astrocytes into neurons in vivo״ cell.com/cell/fulltext/… Why is this negative finding of such interest? mainly because two recent high profile papers reported that PTBP1 knockdown converts glia to neurons to treat #Parkinsons Disease, see following links
Oct 23, 2020 • 7 tweets • 4 min read
Preprint alert: @StefanieAlber et al discovered PTBP1 expression in ADULT peripheral neurons, with roles in sensory function and regeneration, transporting regeneration-associated RNAs to axons. Why is this so interesting? (1/6)
biorxiv.org/content/10.110… The dogma is that PTBP1 should NOT be expressed in mature neurons, as it is downregulated as central neurons mature. So finding it in adult peripheral neurons is intriguing. (2/6)
Jun 30, 2020 • 5 tweets • 3 min read
Manuscript accepted! Congratulations Dr. Marvaldi ⁦@LetiziaMarvaldi⁩ !! With a great team, ⁦@nico_panayotis⁩ ⁦@StefanieAlber⁩ ⁦@TerenzioL⁩ and many others not on Twitter, and a fantastic collaboration with Michael Bader’s group in Berlin. Thanks to all!