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Melina Marmarelis Profile picture
Melina Marmarelis
@MMarmarelis
Thoracic Medical Oncologist, University of Pennsylvania. Lung cancer and mesothelioma. Views are my own.
Apr 18, 2023 • 4 tweets • 4 min read
Some great abstracts in #mesothelioma @AACR2023.

1) Response to CART #meso associated with density of infiltrative TILs with PDL1 and TIGIT as potential targets of resistance. Explains what we see with better outcomes for CART-meso followed by anti-PD1? aacrjournals.org/cancerres/arti… 2) Data on TEAD inhibitors in #meso. No MTD reached. Response does not correlate with NF2 mutation status. Will need to confirm with larger n. @IbiayiMD @curemeso

aacrjournals.org/cancerres/arti…