Mahan Ghafari | ماهان غفاری Profile picture
Postdoc with @katrina_lythgoe @PSIOxford. Virus evolution & Epidemiology | @Ox_DTP @OxfordBiology alum | Tweets in English & Farsi | Usual disclaimers
Feb 21 4 tweets 1 min read
Our paper on persistent SARS-CoV-2 infections (PIs) is now published in @Nature!
Some key findings:
- PIs are much more common than we thought
- PIs are associated with higher odds of long COVID
- Reinfections with genetically similar viruses are rare
nature.com/articles/s4158… Facing the challenge of distinguishing persistent infections from reinfections in our study, we used rare mutations as a key indicator. If two samples from an individual share the same major variant and rare mutation, then they are very likely to represent the same infection