Professor of Medicine, Emerita, Harvard Medical School, now in Pharma, Data Junkie, Grandmother. Policing Twitter for FGF21 disinformation. Opinions are my own.
Feb 28, 2020 • 9 tweets • 2 min read
1. Irreproducibility and the academic scientist: over 30 years I have seen lots of poop published. Poop comes in several flavors. Sometimes see primary data by other lab, looks cherry picked, or poorly done study. Comment in friendly fashion. PI doesn't care, publishes anyway
4. Colleague publishes complete BS clinical study. I know it is BS but don't have time or resources to refute. Gently try tell colleague reagents not validated. He looks at me like I have 2 heads. Spend time time/post-doc effort/funds to refute? What good for trainees career?
Oct 29, 2018 • 18 tweets • 4 min read
An unbiased ketogenic diet tweetorial: I'm an endocrinologist treating individuals with obesity & diabetes. I've done research on effects of ketogenic diets in mice. I have no interest in any entities promoting these diets. Information is intended to educate the curious.
Ketogenic diets (KD) aim at achieving “ketosis.” Ketosis can occur naturally with any successful weight loss regimen. Ketosis is enhanced with fasting or when carbohydrates are limited. During ketosis fat is broken down into fatty acids, which are then broken down to ketones.
