The post-pandemic hospital and mortality burden of COVID-19 compared with influenza: A national cohort study in Denmark, May 2022 to June 2024

COVID-19 was worse than the flu in the first 2 post-pandemic years 2022-2024.


1/10medrxiv.org/content/10.110… A cohort study including residents in Denmark from May 16, 2022, to June 7, 2024, obtained from national registries. Data from PCR+ admissions from COVID-19 and flu. Important; this is limited to those needing medical assistance.
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There is a responsibility to provide accurate information for science/PH reporting. This is even more important for a big-reach account such as @EricTopol.

If it is not your expertise, consult experts and do not make your conclusions, and provide context.

What is wrong?
1/7 @EricTopol The first claim refers to the human challenge study .

There were no cognitive deficits, but the non-standard test appears to show a difference in learning. If that is due to SARS-CoV-2, or infection/bias is not clear .

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https://x.com/Marc_Veld/status/1838625776746344776

https://x.com/Marc_Veld/status/1839042494362796176

RNA-Seq analysis of human heart tissue reveals SARS-CoV-2 infection and inappropriate activation of the TNF-NF-κB pathway in cardiomyocytes

No, not "Nature", also not much infection, and NO conclusion is possible.


1/5nature.com/articles/s4159… Databases were downloaded. Which ones?

A Necessary Role for Increased Biglycan Expression during L1-Mediated Colon Cancer Progression (??)

SARS-CoV-2 Infected Cardiomyocytes Recruit Monocytes by Secreting CCL2 (in virto)

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SARS-CoV-2-specific plasma cells are not durably established in the bone marrow long-lived compartment after mRNA vaccination

Hmmm, you just feel the abuse and misinterpretation hanging in the air....


1/10nature.com/articles/s4159… First of all, you can make an immune response against anything you encounter. The protocol is the same: you select B and T cells, antibodies and memory cells are generated.

This happens for SARS-CoV-2 as well, as is clear from the longitudinal data;

2/10

https://x.com/Marc_Veld/status/1760798635032260745

Zoals gebruikelijk worden er weer alleen naar krantenkoppen gekeken en niet naar de inhoud.

Het betreft hier gegevens vanaf hoofdstuk 3 uit dit proefschrift:
pure.uvt.nl/ws/portalfiles…
Het proefschrift heeft als focus en doel de studie van cytokines gedurende de zwangerschap, en de pandemie gaf een unieke mogelijkheid om dit ook gedurende een bekende en getimede infectie te doen: SARS-COV-2.

Self-reported immune status and COVID-19 associated subjective cognitive functioning in post-COVID-19 syndrome: Examination of an Irish cohort

Important to consider when reading cognitive functioning studies and self-reported immune status studies.


1/10onlinelibrary.wiley.com/doi/10.1002/br… 121 participants were recruited from an online study of cognitive and psychological consequences of post-Covid-syndrome (#longCovd), involving individuals attending a post-COVID-19 clinic + a comparison sample of age- and sex-matched CC who had also been infected with SC2.
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Long COVID and associated outcomes following COVID-19 reinfections: Insights from an International Patient-Led Survey

A pre-print is posted on ResearchSquare only, using an online survey, and disseminated on social media under likeminded. No conclusions should be drawn.
1/8 One author has no affiliation, one only has a university mentioned, and the others are "Patient-Led Research Collaborative". ORCID suggests one author has a PhD in an unknown field, one Masters in Public Policy, and one UofC, SF, Department of Epidemiology & Biostatistics.
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Changes in memory and cognition during the SARS-CoV-2 human challenge study

Paper in eClinicalMedicine, about 34 healthy, unvaccinated, volunteers infected with SARS-CoV-2.


1/9thelancet.com/journals/eclin… It is difficult what to make of it. The differences seem large, yet, it is a small group. Of the volunteers, 18 were considered infected and 16 were not. These tests have biological variability, and differences are often very small as the authors show;

2/9 nejm.org/doi/10.1056/NE…

Neuroinvasive and neurovirulent potential of SARS-CoV-2 in the acute and post-acute phase of intranasally inoculated ferrets

Pre-print, ferrets, without immunity, infected with SARS-CoV-2


1/5biorxiv.org/content/10.110… Evolution of highly pathogenic H5N1 influenza A virus in the central nervous system of ferrets


Pathogenesis of Influenza A/H5N1 Virus Infection in Ferrets Differs between Intranasal and Intratracheal Routes of Inoculation

2/5journals.plos.org/plospathogens/…
linkinghub.elsevier.com/retrieve/pii/S…

The ZC cult is very much like the AV cult. They never come up with something new and constantly need to recycle. There are no new insights that support their doom scenarios.

When corned, personal attacks are all that they left, getting more and more extreme.
1/9 Now this pre-print from 2020, but was eventually published, in 2023, in the highly respected and well-known journal (let me check,.. find notes again, how is it called?.....ah,), "Fortune".

Yeah, if that does not raise some red flags yet.....

2/9

Shared neutrophil and T cell dysfunction is accompanied by a distinct interferon signature during severe febrile illnesses in children

It says dysfunction in the title!!!
What is going on here?


1/9nature.com/articles/s4146… A comparative study with 74 children with multi-system inflammatory syndrome in children (MIS-C) associated with SARS-CoV-2, 30 with bacterial infection, 16 with viral infection, 8 with Kawasaki disease, and 42 controls. (all acute illness)

Comparing different pathogens!
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The priests of the ZeroCovid cult can´t help themselves, they need to keep their flock scared. They pretend to use science, but a quick look tells you it is not. Their claims remain the same; SARS-CoV-2 damages your immune system. It is very, very, wrong to claim this.
1/9 It is wrong because countless studies show your immune system is working fine. But the priests claim your B and T cells are damaged, dysfunctional or even gone! None is true, your B and T cells are there and fully functional.


2/9marcveldhoen.substack.com/p/does-sars-co…

SARS-CoV-2-specific CD8+ T cells from people with long COVID establish and maintain effector phenotype and key TCR signatures over 2 years

Do #LongCovid patients develop robust immunity against SARS-CoV-2? Yes!


1/6pnas.org/doi/10.1073/pn… When we get infected or are exposed to anything that is not part of us, we make an immune response. In LC patients this is not different, but reports show an enhanced activity status, with more antibodies and more active T cells.
Some claim LC patients become immunodeficient.
2/6

Cause-specific excess mortality in Denmark, Finland, Norway, and Sweden during the COVID-19 pandemic 2020–2022: a study using nationwide population data

More excess mortality analysis. What are its cause(s)?


1/7link.springer.com/article/10.100… The excess mortality is seen throughout the world as a result of the pandemic and its aftermath. This study focuses on the scandinavian counties with similar standard of living and democraphics. The causes found were:
-COVID-19: 32,491 deaths 2020–2022, in all countries
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Washing Illness Away: A Systematic Review of the Impact of Nasal Irrigation and Spray on COVID-19

A special one... can you wash a virus away? A virus that invades your cells.... No, don´t fall for it. These studies are not robust at all.


1/5onlinelibrary.wiley.com/doi/10.1002/la… They did a very thorough job. Imagine all those SARS-CoV-2 papers from 1946 to 2019!

These nasal irrigation studies are flawed and published in low journals. No RCTs, low participation, high dropouts. An effect can be attributed to healthy volunteer selection.

2/5

Hmm, nee, dan heb je er niets van begrepen.
Elk COVID-19 vaccin is hetzelfde, behalve kleine aanpassingen die het meer op de huidige variant doen lijken.

De eerste 3, de basis serie, zorgen voor goede selectie en rijping van B en T cellen. Deze beschermen je tegen ziekte.
1/6 Echter, antilichamen verminderen. Een booster zorgt dat deze weer veel worden aangemaakt: je hebt beter bescherming tegen infectie.

In mensen met een verzwakt immuunsysteem helpt het dat B en T cellen ook weer in grotere aantallen worden aangemaakt: beter ziekte bescherming.
2/6

September 2024, and still falling for the table 2 fallacy?

If you do not take the confounders into account, and only look at the initial unadjusted data, you will make a big mistake.

Disinformation kills.
1/10 You can find the explanations of this falacy regarding these particular (previous) studies here:

and here:


2/10factcheck.org/2023/06/sciche…
science.feedback.org/review/clevela…

How Your Immune System Actually Works

Well, not exactly like that. A piece with some truths, and misunderstandings. and misinformation. Part 1 (the first upload was eaten)


1/10okdoomer.io/how-your-immun… Indeed, this is a misunderstanding. You do not need to get ill. You have an immune system. It is there and does not need illness or infection. But, it does need to mature and needs tuning.


2/10 cell.com/immunity/fullt…

How Your Immune System Actually Works

Well, not exactly like that. A piece with some truths, and misunderstandings. and misinformation. Part 2.


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https://x.com/JessicaLexicus/status/1834256524497088924

Indeed, there is cross-inhibition. However, that is only during the infection period. The 1st virus induces an innate response, this (IFN) includes alarm signals, that reduce the risk of a 2nd infection at that time.


2/10

https://x.com/Marc_Veld/status/1834161273522573663

Co-infection dynamics of SARS-CoV-2 and respiratory viruses in the 2022/2023 respiratory season in the Netherlands

What happens if you are infected with 2 coronaviruses?


1/6medrxiv.org/content/10.110… The authors collected symptom data and nose- and throat samples from symptomatic people during the 2022/2023 respiratory season in a large participatory surveillance study in the Netherlands, and tested these for 18 respiratory viruses including SARS-CoV-2.
2/6

Divergent inflammatory and neurology-related plasma protein profiles in individuals with long COVID following primary and breakthrough SARS-CoV-2 infections

Not much to make of this.


1/4medrxiv.org/content/10.110… The project is an analysis for potential plasma biomarkers of LC. Samples from October 2020 to April 2023: COVID-19 recovered (21), LongCovid (12), or SARS-CoV-2 naïve (24). Vaccination and breakthrough infections (BTI) as variables in a 2nd cohort.
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