Brain development and function @KingsCollegeLon Also science policy and, occasionally, food & drinks. Blame Oscar for the views expressed here.
Nov 24, 2022 • 8 tweets • 7 min read
1/8 Are all synapses created equal? @clembrnrd in @Rico_lab and @MarinLab has found that the building of new synapses is controlled in a cell-type and even synapse-type-specific manner. This is the story @ScienceMagazinescience.org/doi/10.1126/sc… ⬇ thread @dev_neuro@MRC_CNDD2/8 We approached this question by investigating the wiring of PV+ and SST+ interneurons in the mouse neocortex. These cells have highly related developmental trajectories but play very different roles in adulthood, making them an attractive model for studying synapse specificity