1/4 In a very long blog, Dr. Malcolm Kendrick concludes that COVID-19 exposed a broken medical research system, where fraud, unreliable data, and biased narratives undermine trust in science. He believes the pandemic was not a conspiracy but a “gigantic earth-shaking cock-up” /2 2/4 followed by an unspoken cover-up. No surprises there ! The virus likely escaped from a Wuhan lab, was exaggerated in lethality to justify drastic measures like lockdowns, and led to rushed mRNA vaccines with questionable oversight. /3

1/6 People who have poor oral health (such as gum disease or tooth decay) have higher rates of cardiovascular disease such as heart attack or stroke than people with good oral health. The bacteria that infect the gums and cause gingivitis and periodontitis
/2 2/6 travel to blood vessels elsewhere in the body where they cause blood vessel inflammation and damage; tiny blood clots, heart attack and stroke may follow. Supporting this idea is the finding of remnants of oral bacteria within atherosclerotic blood vessels
/3

1/5 The brain, composed of 60% fat, is the body's fattiest organ. Glial cells utilize mevalonate to produce cholesterol, which is abundant in brain tissue, to maintain and repair myelin through rapid replication. Statin drugs, which lower cholesterol, impair myelin repair.
/2 2/5 Statins also block nerve cells from making isopentenyl adenine, essential for DNA replication. Myelin, an insulating sheath composed of 70% fat and 30% protein surrounding nerves in the brain and spinal cord, relies heavily on cholesterol

/3

1/6 For years, doctors have prescribed statins based on the belief that elevated LDL is a major risk factor for cardiovascular disease. This is a tragic error. Doctors have failed their patients because LDL, a cholesterol carrier, is not a "bad" molecule. /2 2/6 However, when LDL undergoes oxidative damage, often due to reactive oxygen species, it transforms into oxidized LDL, a "damaged" molecule, which is more prone to being taken up by macrophages, forming foam cells that can contribute to atherosclerosis /3

1/12 HYPERTENSION: Statins act as mitochondrial toxins that impair muscle function in the heart & blood vessels through depletion of Coenzyme Q10 and heme A', and thereby ATP generation. ATP provides energy to drive & support many processes in living cells, such as muscle /2 2/12 contraction, nerve impulse propagation, and chemical synthesis. CoQ10’s effectiveness in lowering blood pressure has been known since the 1970’s. It does so in a number of ways. First as an antioxidant it can neutralize peroxynitrite free radicals. /3

1/6 I believe all medications should be studied for their effect on mitochondrial function, and this includes food additives, pesticides & personal care products. You wouldn't believe how many medications damage cell mitochondria - listed below are some known ones: /2 2/6 Analgesics (including Aspirin), Angina drugs, Anti-anxiety, Anti-arrhythmic, Antibiotics, Antidepressants, Antipsychotics, Cancer drugs, Cholesterol lowering drugs (Statins), Dementia meds, Diabetes meds (Metformin included), Epilepsy meds & Parkinson's disease meds. /3

1/4 What a wise doctor. I used Serrapeptase after experiencing a blood clot in a varicose vein. My doctor prescribed Warfarin. To hell with that ! Serrapeptase did the job within 7 days. No "side effects" I do wonder how many people would still be alive today /2

https://twitter.com/msdkfjhsfd8/status/1969867276485636254

2/4 if they had used Serrapeptase, instead of Statins, and dodged the Covid vaccine. Serrapeptase is a natural proteolytic enzyme that acts like a 'pac man' on arterial plaque. There is good evidence that Serrapeptase reduces arterial calcification and inflammation /3

1/8 Please don't be fooled. There is no such thing as a statin “side effect”. Statin toxicity is a direct and predictable effect of blocking mevalonate by inhibiting the enzyme HMG-CoA Reductase, which makes it. /2 2/8 Statin poisoning is a sign that certain cells cannot mutate by increasing reductase to overcome the direct cell toxic effect of the Mevalonate blockade of Statins. Pharmaceutical companies knew this back in 1980. /3

1/5 @realDonaldTrump's Crestor and Ezetimibe have his LDL at 51 mg/dL. It looks good on paper, but is it ? Ultra-low LDL may weaken immunity, raising infection risk. His leg swelling from venous insufficiency is also concerning.
/2 2/5 Are statins harming his heart & arteries instead of helping ? Trump has been on Crestor since 2016, starting at 10 mg, increased to perhaps 20–40 mg in his first term, now back to 10 mg with Ezetimibe. LDL at 51 mg/dL may seem ideal, but low CoQ10 could weaken his heart /3

1/4 Statins & Muscle Pain: Class Effect, Not a Side Effect: Statins are widely prescribed to lower cholesterol, but muscle pain is a class effect due to their mechanism. Statins inhibit HMG-CoA reductase, blocking cholesterol synthesis. This deprives cells of mevalonate, /2 2/4 a critical compound. Mevalonate deprivation isn’t trivial, it can damage cell mitochondria, disrupt muscle membranes, and even cause cell death. This isn’t just a “side effect” unique to one statin; it’s a class effect shared by all statins due to how they work. /3

1/9 Chronic inflammatory diseases, such as rheumatoid arthritis, lupus, psoriasis, and infections such as periodontal disease (p.gingivalis), & HIV, are associated with an increased risk of heart disease. Patients with these disorders also have an increase in coronary artery /2 2/9 calcium measured by CT & carotid intima media thickness measured by ultrasound. WHY ?? Because inflammation & infections induce a variety of alterations in lipid metabolism that may initially DAMPEN inflammation or fight infection, but if chronic, can contribute to the /3

1/8 One of the vital roles of Vitamin C is to act as an antioxidant to protect cellular components from free radical damage. Vitamin C has been shown to scavenge free radicals directly in the aqueous phases of cells and the circulatory system. /2 2/8 Unlike Statins, Vitamin C has been proven to protect membranes & other hydrophobic compartments from such damage. Human subjects with low Vitamin C levels have been reported to have higher amounts of lipid peroxides in plasma than do subjects with high vitamin C levels. /3

1/5 What benefit ? 🙄 The study linking statins’ calcification effect to mortality benefits relies heavily on correlational data, oversimplifying the role of calcification. It ignores thresholds, trade-offs, and confounders, while neglecting long-term risks and contradictory /2

https://twitter.com/AlexJLeaf/status/1954410838951120924

2/5 evidence like apoptosis or metabolic effects. The conclusion, that statins’ calcification is clearly beneficial, lacks robust support & misrepresents cardiovascular disease complexity. A stronger study would directly test the calcification hypothesis and address /3

1/4 Metabolism is how cells "breathe", We breathe air into our lungs so that oxygen is delivered to our cells for metabolism. Anything that obstructs this process "suffocates cells" and CoQ10 is as essential as oxygen.. Skeletal & heart muscle cells have a very high demand for /2 2/4 CoQ10. Muscle cell damage (myopathy) and muscle cell death (rhabdomyolysis) are the most commonly reported Statin injury. Three years after FDA approval of Lovastatin, Merck decided that statin-blockade of CoQ10 synthesis was causing Statin Myopathy. /3

1/5 Statins are widely prescribed to lower cholesterol, but do doctors truly understand how they work ? Relying on "empirical data" without questioning the mechanism of action is a risky approach for patients. /2 2/6 Statins block the Mevalonate pathway, a vital process in cells. This pathway produces biochemicals essential for cell survival and function. Disrupting it does more harm than good. /3

1/7 Nobel Prize winning Neuroscientist Eric Kandel says "We are who we are because of what we learn and what we remember. Who am I, then, if my memory is
impaired ? People who take Statins very often complain about “brain fog’, inability to think clearly, memory loss, /2 2/7 depression, etc. Even the FDA warns on Statin labels that people have developed memory loss or confusion while taking Statins. Statins are - Thief of memory (here’s how): The basic unit of communication in the nervous system is the nerve cell (neuron). Each nerve cell /3

1/4 “Many of the symptoms displayed during the course of Mustafa’s illness—symptoms that eventually led to a diagnosis of ALS, motor neurone disease—are well documented side effects of statins and are listed in the leaflet that accompanies the tablets. /2 2/4 With such similarities in mind, it seems wise to monitor statin-intolerant patients closely and to weigh up carefully whether the disadvantages of taking these drugs outweigh the benefits for these patients. /3

1/4 Animals will keep eating until they satisfy their protein requirements, so a diet low in protein naturally stimulates overeating. This is why the most effective strategy for reversing Metabolic Syndrome is increasing protein while reducing carbohydrates. /2 2/4 This way of eating tends to stabilize hunger and satiety hormones incredibly well. It also decouples your mitochondria so they become active and eager to burn off energy as heat, increases your lean muscle mass, your metabolism, and your bone density. /3

1/6 Back in 2008 nobody prepared me for what I was about to find out about statins. I was naive, trusting, I believed everything people told me, I am longer that person. Researching statins changed all that. It started when my father was prescribed Atorvastatin post a 2/6 minor stroke. The stroke did little harm, but the medication post stroke destroyed his health. I recall my father telling me he couldn't think any more since he was on these drugs, and he also suffered from muscle damage and acute pancreatitis while on them. /3

1/10 I’m appalled at the response @RLauvray
received from his doctor for refusing statins. Telling him to “get another doctor” is lazy and incurious, ignoring potential harms of statins and using threats to push a drug. This can also happen when doctors are incentivized to /2

https://twitter.com/RLauvray/status/1949984209042276841

2/10 promote cholesterol-lowering meds. Rob, you deserve better. Here’s a thread to help you improve insulin sensitivity naturally.
First, diet is key. Adopt a Low-Carb, High-Fat (LCHF) or Ketogenic diet to stabilize blood sugar. Ditch sugars, fruit juices, sodas, /3

1/8 Statins lower cholesterol by inhibiting HMG-CoA reductase, an enzyme in the liver that drives cholesterol synthesis. Statins can raise blood glucose and contribute to insulin resistance. Here's how: The inhibition of HMG-CoA reductase reduces the production of mevalonate, /2 2/8 a key molecule in the cholesterol synthesis pathway. This also lowers levels of downstream molecules called isoprenoids, like geranylgeranyl pyrophosphate which are important for cell signaling. GGPP is critical for prenylation, a process that activates small proteins. /3