Marion Holman Profile picture
The TRUTH about Statins, formerly @holmanm Info is provided for educational purposes only & should not be considered as medical advice. (NO DM's please)
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Nov 8 6 tweets 2 min read
1/6 Doctors, uninformed of how Statins really work, have clung on to the "pleiotropic effect" of Statins, rather than what Statins really are - Mitochondrial Toxins. For example, Statins suppress cell cycles of white blood cells. Patients with autoimmune disease sometimes /2 2/6 have immune "flare ups" with elevated white blood cell counts. Because Statins inhibit white blood cell turnover, people with autoimmune diseases appear to be doing better (on paper) because their white blood cell counts are down ! Drs WRONGLY conclude that Statins /3
Nov 7 4 tweets 1 min read
1/4 New research published in the journal PLoS indicates that the use of statins is associated with an increased prevalence of microalbuminuria, a well-known marker of vascular dysfunction, affecting both cardiovascular and kidney disease risk.
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2/4 "Microalbuminuria is known to double the risk for a cardiovascular event in patients with type 2 diabetes mellitus and is a marker for endothelial function; endothelial dysfunction may, in fact, be far more significant than elevated blood lipids in determining
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Nov 7 5 tweets 1 min read
1/5 I've seen Warfarin prescribed alongside a Statin on many occasions. What a great way to calcify arteries. A long-term adverse effect of warfarin therapy is vascular calcification. The proven mechanism is warfarin’s near-shutdown of the body’s vitamin K recycling capacity. /2 2/5 As the availability of functional (that is, electronically reduced) vitamin K via the K cycle becomes limited, whether from warfarin therapy, from dietary inadequacies, or from other factors, the body progressively is deprived of vitamin K’s carboxylation capacity. /3
Nov 6 9 tweets 2 min read
1/9 Nobel Prize winning Neuroscientist Eric Kandel says - "we are who we are because of what we learn and what we remember". Who am I, then, if my memory is
impaired🤔 ? People who take Statins very often complain about brain fog, inability to think clearly, memory loss, /2 2/9 depression. Even the FDA warns on Statin labelling that people have developed memory loss or confusion while taking Statins. Statins are - 'Thief of memory'
Here's how. The basic unit of communication in the nervous system is the nerve cell (neuron).
Each nerve cell /3
Nov 6 4 tweets 1 min read
1/4 Metabolic syndrome is a cluster of risk factors for Cardiovascular disease and Type 2 diabetes which occur together more often than by chance alone.
These risk factors include:
a) A distinct dyslipidemic phenotype (raised Triglycerides and low HDL);
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b) Raised blood pressure;
c) Altered glucose metabolism;
d) Impaired fasting insulin;
d) Central obesity.

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Nov 5 4 tweets 1 min read
1/4 Eggs are a SUPERFOOD. Eggs improve blood lipid profiles, insulin sensitivity, and glucose response. Lutein, zeaxanthin, and ACE inhibitory tripeptides from egg have been shown to have benefits against glucose and insulin intolerance, oxidative stress, /2 2/4 and inflammation. It's all GOOD !!
When you eat eggs the composition of LDL particles is significantly altered; the core becomes enriched in esterified cholesterol at the expense of Triglycerides. /3
Nov 4 11 tweets 2 min read
1/11 I’ve been reading "Mitochondria & the Future of Medicine. The Key to Understanding Disease, Chronic Illness, Aging, and Life Itself"
By Lee Know
A chapter on mitochondrial involvement in Neurodegeneration provides evidence that Statins may be causal in many serious
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2/11 diseases such as ALS, Parkinson’s Disease, Alzheimer’s disease & MS. Statins block Mevalonate synthesis, which lowers levels of CoQ10, an essential compound for mitochondrial energy production. I’ve witnessed many Statin users receive a diagnosis of ALS & Parkinson's
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Nov 3 6 tweets 2 min read
1/6 The practice of medicine has completely lost its way. Remedies that treat symptoms or 'numbers' on a lipid profile, have replaced the search for cures. Doctors no longer try to establish the root cause of disease. There is no profit in doing so. /2 2/6 The problem is much more pervasive and sinister than that. What happened to "first do no harm" ?
That tenet has been so utterly corrupted by the pharmaceutical industry that it no longer plays into the practice of medicine. Bribes are not necessary. /3
Nov 2 4 tweets 1 min read
1/4 Inhibition of cholesterol biosynthesis by Statins prevents proper epithelial cell development within the crystalline lens of the eye, which requires high levels of cholesterol to maintain its transparency.
/2 2/4 Statins block CoQ10 found in the retina. Studies have shown that treatment with CoQ10 can improve visual function in patients with age-related macular degeneration. In glaucomatous models, CoQ10 exposure protected ganglion cell death from environmental stress;
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Nov 1 6 tweets 1 min read
1/6 Insulin has a profound effect on Cholesterol.
Insulin turns up the Cholesterol making machinery by turbocharging the activity of the enzyme that actually controls cholesterol manufacturing in your body. This enzyme is called HMG-CoA Reductase. /2 2/6 You can improve your lipid profile by simply lowering your insulin levels. By doing so you avoid all of the serious "direct effects" of taking Statin drugs, and will experience improved cardiovascular health. /3
Oct 31 5 tweets 1 min read
1/5 In 1980, Brown and Goldstein (physician-scientists who discovered the LDL receptor) clearly reported that Statins block Mevalonate and not just Cholesterol. This mutates cells into what they called "Mevalonate auxotrophs" (mutant cells deficient in Mevalonate)
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2/5 In a 1984 paper, Merck reported that the higher the Statin dose, the more Reductase is elevated to overcome the potentially lethal effects of blocking Mevalonate. They even photographed the resultant structural damage.
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Oct 27 6 tweets 1 min read
1/6 Lipoproteins are globular micelle-like particles consisting of an amphipathic protein coat, free cholesterol, and phospholipids surrounding a hydrophobic core containing cholesterol esters and Triglycerides. Cholesterol is a molecule with a double bond in its structure /2 2/6 Here⤵️ Image
Oct 14 8 tweets 2 min read
1/8 It is no surprise that drugs which raise HDL are of no benefit, and sometimes downright dangerous, but useful to see it confirmed in this paper. There is an association between low HDL and cardiovascular disease because they have a common cause, not because one causes /2 2/8 the other. That cause is a diet high in sugar, seed oils and carbohydrate. Over a period of 2.5 million years prehistoric man became genetically adapted to eating 5% carbohydrate, 75% fat and 20% protein. Since the start of agriculture approx 12,000 years ago we have /3
Oct 8 8 tweets 2 min read
1/8 Prior to the introduction of Statin drugs there were a number of studies done in which cholesterol was successfully lowered by other drugs, notably Fibrates. These drugs actually lowered cholesterol quite well.
If lowering cholesterol does in fact prevent
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2/8 heart disease or strokes, we should see a significant reduction in heart attacks and strokes anytime we successfully lower it, regardless of the particular drug or diet used to accomplish this. (agreed ??) Now get this: Investigations of the cholesterol lowering
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Oct 7 6 tweets 2 min read
1/6 “Doctors and patients need good quality scientific evidence in order to make informed decisions, but for decades they have been misled by directives based on corrupt clinical studies, which have been knowingly altered to exaggerate the benefits of their drugs and to
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2/6 minimise their secondary effects. When their findings are carefully analyzed, nothing remains of their claims”
- Michel de Lorgeril Cardiologist & Author of Cholesterol and Statins: Sham science and bad medicine.
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Oct 4 6 tweets 2 min read
1/6 Studies by researchers at the University of Warwick have demonstrated that Statins lower blood pressure.
A heart that pumps less efficiently due to CoQ10 deficiency should pump blood at a lower pressure. Statin trials by the drug companies have touted that Statins lower /2 2/6 blood LDL levels as well as the incidence of stroke and cardiovascular events. Stroke and LDL levels are not connected, but lower blood pressure does decrease the risk of stroke and heart attacks.

A weakening of the heart muscle with Statins due to CoQ10 blockade /3
Oct 3 7 tweets 2 min read
1/7 Informed consent allows you to participate in your own healthcare. It enables you to decide which medical treatments you do or do not want. If your Doctor prescribes a Statin drug, are you given informed consent ? Does your Doctor inform you that Statin drugs block
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2/7 Mevalonate which every cell normally makes to replicate. If cells cannot replicate they die ? I think not.
The Mevalonate pathway, is also known as the Isoprenoid pathway
Isoprenoids are made from 5-carbon “isoprene” units that are “prenylated” which means they have fat
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Oct 2 8 tweets 2 min read
1/8 Merck Scientists withheld knowledge that blocking Mevalonate is deadly. To gain approval of Lovastatin they said the “side effects” were due to an unknown mechanism. Furthermore, Merck had inserted so many of their own people into the process that no willing and
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2/8 knowledgeable FDA employee was even there to challenge them. With Merck employees and advisors in the majority on the FDA committee, Merck could have told the whole truth and Lovastatin would have been approved anyway. The lies were not meant to acquire
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Oct 1 8 tweets 2 min read
1/8 Lipid theorists reason that the lower the blood LDL cholesterol the better. They conveniently ignore the process of cholesterol oxidation. Cholesterol, oxidation and Cardiovascular disease go hand-in-hand.

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2/8 The causal relationship between oxidizers and cardiovascular disease has been known for a long time but has been suppressed. Oxidizers are electron thieves, they work by stealing electrons from
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Sep 29 7 tweets 2 min read
1/7 Anyone think the practice of medicine has lost its way ? Remedies that treat symptoms and only offer some relief have replaced the search for cures. Scant attention is paid to the root cause of disease. However, the problem is more pervasive and sinister than that. /2 2/7 The first & most basic tenet of medicine is "to do no harm". That tenet has been so utterly corrupted by the pharmaceutical industry that it no longer plays into the practice of medicine. Bribes are not necessary. The purchase of influence is done in full public view /3
Sep 28 11 tweets 2 min read
1/11 The truth about the toxicity of Statin drugs is staring us in the face. For years I've been aware that Statins are causal in serious autoimmune conditions such as ALS, Parkinson’s, Alzheimer’s, Lupus, etc. My Uncle died of ALS 12 months of using 80mg of Lipitor as did a /2 2/11 friend in Canada using the same dose of Statin for two years. When you fully understand the mechanism of action of Statin drugs it is patently obvious that Statins are causal in these conditions. /3