Head Department of Internal Medicine @Radboudumc. Professor fighting venous thromboembolism. Pregnancy, thrombosis, thrombophilia. Council @ISTH. Feminist.
Oct 28, 2022 • 9 tweets • 3 min read
Intermediate-dose versus low-dose low-molecular-weight heparin in pregnant and post-partum women with a history of venous thromboembolism (Highlow study): an open-label, multicentre, randomised, controlled trial thelancet.com/journals/lance…
We found that the higher dose did not reduce the risk of recurrent #VTE during the entire study period (Pregnancy plus postpartum period), which was unexpected and perhaps due to an over-enthusiastic sample size calculation…