#ASPNFOAM #tweetorialalert
Let's talk Goodpasture disease in children 🙅♂️#oldtimersname 🙈#misnomer ↗️refuted by the doc👨⚕️himself ‼️
Anti glomerular basement membrane (Anti GBM) disease with or without lung involvement #SPECTRUM #AntiGBM #NephTwitter #PedNeph @ASPNeph
#QUIZTIME
The following differentiates pediatric anti-GBM disease from adult disease except ❓
Aug 30, 2022 • 21 tweets • 13 min read
1/This July’s @aspneph pathology webinar was all about pediatric Antineutrophil Cytoplasmic Antibody (ANCA)- associated vasculitis (AAV). Let's kick off this pediatric AAV tweetorial✍️with a quick question #NephTwitter
🤔 What is the role of ANCA antibodies❓
2/ ✅Diagnostic marker and Pathogenic in nature
▶️ Proteinase-3 (PR3) and Myeloperoxidase (MPO) antigens are sequestered in neutrophil primary granules
▶️ Antigen exposure triggers immune response leading to endothelial activation linkinghub.elsevier.com/retrieve/pii/S…