Monique van der Wijst Profile picture
Jun 7, 2022 8 tweets 5 min read
Excited to share our paper in @NatureComms where we present the 1M-scBloodNL study in which we profiled 1.3M immune cells from 120 healthy individuals, longitudinally exposed to 3 different pathogens doi.org/10.1038/s41467… @UMCGgenetica #scRNA 1/8 We mapped differential expression, cis-eQTLs and response-QTLs in 6 major immune cell types and 10 subcell types. This indicated that the genetic control of the gene expression response upon pathogen stimulation was more cell-type- than pathogen-specific. 2/8