A 🧵on STRONG-HF 💪🏾🫀

⭐️The first randomized trial to show the immense benefits of a comprehensive high-intensity med-titration program with #HF GDMT

❓How did the investigators achieve an 8.1% ARR in HFH/mortality at 6 months❓

Let’s see what we can learn 👇🏾🧵 First let’s take a look at the inclusion and exclusion criteria.

You’ll note:
👉🏾must have SBP > 100, HR >60, K <5.0, GFR > 30
-this eliminates many patients unlikely to tolerate aggressive titration

At baseline still a sick cohort:
-66% NYHA 3 or more
-avg NT-proBNP 7110