Currently, what is your opinion on using dexamethasone?
2/ Trial info:
▶️RCT, open-label, adaptive
▶️6,425 pts enrolled
▶️Dex 6mg daily for 10d (PO or IV) v usual care (1:2 ratio, respectively)
▶️176 🏥in UK
▶️Prim Outcome: OS
🔑Intention-to-treat
🔑Pre-specified stats plan
🔑Not randomized by O2 status
▶️ Can likely stick to one residency - MP - if you interview enough places will be OK
▶️ If you're geographically restricted, may make sense
▶️ PDs will not view it as a negative thing if you dual apply
21/