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Raj Rajnarayanan Profile picture
Raj Rajnarayanan
@RajlabN
Assistant Dean of Research and Associate Professor, NYITCOM at Arkansas State University | My Tweets are my own
Dame Chris🌟🇺🇦😷 #RejoinEU #FBPE #GTTO🔶️ Profile picture Sue Strong @strong_sue@mastodon.sdf.org 🇺🇦 Profile picture Christina Cat Profile picture 5 subscribed
Sep 26 • 10 tweets • 5 min read
#COVID19 #VariantDashboard - #USA

#SARSCoV2 Lineages #21DAYTRENDS

XBB.1.16.6 (9.2%)
FL.1.5.1 (9.0%)⬆️
EG.5.1.1 (8.2%)
HV.1 (6.6%)⬆️
EG.5.1 (6.1%)
EG.5.1.3 (3.6%)
XBB.1.16 (3.5%)
EG.5.1.4 (3.3%)
XBB.1.16.11 (3.0%)

Tracker: | 09/25/23

1/n tinyurl.com/mryj4uu7
Image Sequence count by US States

A total of 2727 sequences were submitted with specimen collection dates on or after 09/04/2023 (of which 278 (~10%) were collected via airport surveillance)

#NY has uploaded a lion's share of sequences this period

2/n Image
Sep 11 • 4 tweets • 1 min read
@3Whatevah @outbreakupdates @siamosolocani @yunlong_cao Mutations in the spike protein can change its shape or structure, making it less recognizable to antibodies generated in response to previous infections or vaccinations. 2/n @3Whatevah @outbreakupdates @siamosolocani @yunlong_cao Immune evasive mutations can potentially reduce the efficacy of vaccines. If a variant with such mutations becomes dominant and vaccines are less effective against it, booster shots or updated vaccines targeting the new variants may be needed to maintain protection. 3/n
Sep 8 • 11 tweets • 2 min read
BA.2.86* #Pirola Updates

#UnitedKingdom has uploaded 27 sequences to GISAID today- majority of these sequences were from a single care-home outbreak.

While this is not surprising for a lineage like BA.2.86*, the attack rate of ~87% is still high.

1/n Protection of vulnerable residents in Care homes should be part of a broad National plan (to avoid domino effect)

1. All eligible residents and staff must be "fully vaccinated"

* update the definitions of "fully vaccinated" to include booster with appropriate guidance

2/n
Sep 2 • 9 tweets • 2 min read
XBB.1.5 booster and recent infections may offer some protection against BA.2.86 (#Pirola)

Based on previously available data, they are expected to work against current top lineages EG.5.1 (#Eris), FL.1.5.1 (#Fornax) etc

Get boosted as soon as XBB.1.5 booster is available

1/n Vigilantly monitoring BA.2.86 sub-lineages and emerging recombinants of the next generation, which might exhibit greater infectivity than their original lineages is key!

2/n
Aug 24 • 11 tweets • 5 min read
#COVID19 #VariantDashboard - #USA

Top #SARSCoV2 Lineages #21DAYTRENDS

XBB.1.16 (6.8%)
FL.1.5.1 (6.7%)
XBB.1.16.6 (6.1%)
EG.5.1.1 (5.6%)
XBB.1.5 (4.8%)
EG.5.1 (4.6%)
XBB.1.16.1 (3.8%)
GJ.1.2 (2.9%)

Tracker: | 08/23/23

1/n tinyurl.com/mryj4uu7
Image Sequence count by US States

A total of 2955 sequences were submitted with specimen collection dates on or after 08/02/2023 (of which 177 (~6%) were collected via airport surveillance)

#TX, #NY and #CA have uploaded a lion's share of sequences this period

2/n Image
Aug 17 • 5 tweets • 1 min read
#SARSCoV2 #EarlyAnalysis #BA2

Spike mutational profile of newly designated BA.2.86 (BA.X) spotted by @shay_fleishon and @LongDesertTrain

BA.2.86 vs XBB.1.5 (This season's vaccine antigen selected by @US_FDA/@CDCgov)

Closely monitored by #VariantHunters and more recently @WHO Image BA.2.86 already has the mutation of the past two seasons Spike F486P (in almost all the top circulating lineages now)

Still doesn't contain the mutation of the current season Spike F456L or "FLip" (Spike F456L/L455F)

Variant Hunters are closing monitoring this lineage group
Jun 4 • 7 tweets • 8 min read
Tracking #SARSCoV2 #Lineages - Globally

Top lineages -#20DayTrends (#G20):

XBB.1.5 (16.5%)⬇️
XBB.1.16 (10.5%)⬆️
XBB.1.9.1 (7.3%)
FL.4 (4%)
EG.1 (3.6%)
XBB.1.16.1 (3.4%)
XBB.1.9.2 (3.2%)
XBB.2.3.2 (2.6%)
FL.2 (2.5%)
FU.1 (2.1%)

public.tableau.com/app/profile/ra…
Updated 6/4/23 Image Granular details #Global #20DayTrends

This analysis includes all designated #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 05/15/2023 (6,574 sequences) Image
Jun 3 • 8 tweets • 9 min read
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#21DAYTRENDS*):

28.4% XBB.1.5
8.1% XBB.1.16
4.4% XBB.1.16.1
4.4% XBB.1.9.1
3.3% EU.1.1.1
2.8% XBB.1.9.2

[Includes ~42% Airport surveillance seqs]

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7| 06/02/23

1/n Sequence count by US States

A total of 999 sequences were submitted with specimen collection dates on or after 05/12/2023 (of which 421 were collected via airport surveillance)

2/n Image
Jun 2 • 8 tweets • 9 min read
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#21DAYTRENDS*):

29.7% XBB.1.5
8.5% XBB.1.16
5.3% XBB.1.9.1
3.8% XBB.1.16.1
3.5% EU.1.1.1
2.4% FL.4

[Includes ~43% Airport surveillance seqs]

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7| 06/01/23
1/n Sequence count by US States

A total of 949 sequences were submitted with specimen collection dates on or after 05/11/2023 (of which 410 were collected via airport surveillance)

2/n Image
May 25 • 7 tweets • 8 min read
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

31.5% XBB.1.5
11.8% XBB.1.16
5.3% XBB.1.9.1
2.5% XBB.1.16.1
2.1% FL.4
2.1% XBB.1.5.49

[Includes ~44.5% Airport surveillance seqs]

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7| 05/24/23

1/n Image Sequence count by US States

A total of 527 sequences were submitted with specimen collection dates on or after 05/09/2023

2/n Image
May 24 • 7 tweets • 8 min read
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):
30.3% XBB.1.5
11.0% XBB.1.16
5.9% XBB.1.9.1
3.4% XBB.1.16.1
1.8% FL.4
1.6% EG.2
1.4% XBB.2.3.2

[Includes ~49% Airport surveillance seqs]

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7| 05/23/23
1/n Image Sequence count by US States

A total of 564 sequences were submitted with specimen collection dates on or after 05/08/2023

2/n Image
May 23 • 7 tweets • 8 min read
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

37.9% XBB.1.5
9.2% XBB.1.16
4.4% XBB.1.9.1
2.8% XBB.1.16.1
2.2% XBB.1.9.2
2.0% XBB.2.3.2

[Includes ~26% Airport surveillance seqs]

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7| 05/22/23

1/n Image Sequence count by US States

A total of 497 sequences were submitted with specimen collection dates on or after 05/07/2023

2/n Image
May 2 • 17 tweets • 16 min read
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

56.2% XBB.1.5
6.1% XBB.1.9.1
4.5% XBB.1.16
2.2% XBB.1.5.1
2.1% XBB.1.9.2
1.4% XBB.1.5.13
1.4% XBB.1.5.15
1.4% XBB.1.5.17

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 05/01/23

1/n Image #COVID19 #VariantDashboard - #USA
[without sequences from "Airport Surveillance"]

Top lineages (#15DayTrends):

XBB.1.5 (61.7%)
XBB.1.9.1 (5.5%)
XBB.1.16 (2.4%)
XBB.1.5.1 (2.3%)
XBB.1.5.13 (1.6%)
XBB.1.5.17 (1.6%)
XBB.1.9.2 (1.6%)
XBB.1.5.15 (1.3%)
FD.2 (1%)

2/n Image
May 1 • 4 tweets • 3 min read
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally

Total Sequences : 8,182 (circulating in 43 countries)

Tracker:public.tableau.com/app/profile/ra…

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance

Updated:05/01/23 Image Tracker now includes all the designated XBB.1.16* sub-lineages

May 1 • 18 tweets • 16 min read
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

49.7% XBB.1.5
8.3% XBB.1.16
8.3% XBB.1.9.1
2.3% XBB.1.9.2
2.1% XBB.1.16.1
1.6% XBB.1.5.1
1.4% XBB.2.3

>> Low Sequence Count <<
#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/30/23

1/n #COVID19 #VariantDashboard - #USA
[without sequences from "Airport Surveillance"]

Top lineages (#15DayTrends):

XBB.1.5 (61.1%)
XBB.1.9.1 (8.0%)
XBB.1.16 (3.5%)
FL.2 (1.7%)
XBB.1.5.1 (1.7%)
XBB.1.5.17 (1.7%)
XBB.1.9.2 (1.4%)
XBB.1.5.15 (1.2%)

2/n Image
Apr 30 • 8 tweets • 10 min read
Tracking #SARSCoV2 #Lineages - Globally

Top lineages -#20DayTrends (#G20):

XBB.1.5 (36.6%)⬇️
XBB.1.9.1 (11.5%)⬆️
EG.1 (4.7%)⬆️
XBB.1.16 (4.4%)⬆️
XBB.1.9.2 (3.1%)
XBB.2.3 (1.8%)
XBB.1.5.13 (1.6%)
XBB.1.16.1 (1.5%)

public.tableau.com/app/profile/ra…

Updated 04/29/23 Image Granular details #Global #20DayTrends

This analysis includes all designated #SARSCoV2 sequences submitted to @GISAID with sample collection dates on or after 04/09/2023 (14,137 sequences) Image
Apr 21 • 4 tweets • 4 min read
#SARSCoV2 #VariantProportions - #USA |04/21/23

New @CDCgov #Nowcast estimates:

Top circulating lineages:

XBB.1.5 (73.6%)⬇️
XBB.1.16 (9.6%) ⬆️
XBB.1.9.1 (7.9%)
XBB.1.9.2 (2.9%)
XBB.1.5.1 (2.2%)
FD.2 (1.6%)
XBB (1%)

covid.cdc.gov/covid-data-tra…

1/n Image Over all trends are consistent with #15DayTrends (based on sequences uploaded in the public databases)

XBB.1.5 is still at the top; followed by XBB.1.16 & XBB.1.9.1

Expect XBB.2.3 to feature in the @CDCgov dashboard soon!



2/n
Apr 21 • 17 tweets • 17 min read
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

52.8% XBB.1.5
9.5% XBB.1.16👀
4.7% XBB.1.9.1
2.6% XBB.1.16.1👀
2.3% XBB.1.9.2
1.3% EG.1
1.2% XBB.2.3
1.2% XBB.1.5.15

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/20/23

1/n Image Use "Airport Surveillance" (AS) pull-down menu to easily track variant proportions Nationally or by State with or without AS sequences

Top lineages (#15DayTrends w/o AS seqs):

XBB.1.5 (64%),
XBB.1.9.1 (3.8%),
XBB.1.16 (3%),
XBB.1.5.19 (1.6%),
XBB.1.9.2 (1.4%)

2/n Image
Apr 20 • 4 tweets • 3 min read
Tracking #SARSCoV2 lineage XBB.1.16* (#Arcturus) over time - Globally

Total Sequences : 4,837 (circulating in 37 countries)

Tracker: public.tableau.com/app/profile/ra……

Note: Recent Epi weeks are incomplete; Includes seqs from targeted & Airport surveillance
Updated:04/20/23 Image New entrant: #Bulgaria Image
Apr 20 • 9 tweets • 7 min read
#VariantDashboard #India - #30DayTrends

Top lineages:

XBB.1.16 (62.8%)
XBB.1.16.1 (9.2%)
XBB.2.3 (7.8%)
XBB.1.16+NS3_V13L (4.7%)
XBB.1.5 (3.2%)
XBB.2.3.2 (3%)
XBB.1.9.1 (1.4%)
XBB.1 (1.3%)
XBB.2.3.4 (1.3%)

Tracker:public.tableau.com/app/profile/ra…

Updated: 04/19/23 Image Granular details - #VariantDashboard #India - #30DayTrends

XBB.1.16* (76.6%) is still the dominant variant group in #India, followed by XBB.2.3* (14%)

Note: Data limited to few States that are sequencing and rapidly submitting data Image
Apr 20 • 18 tweets • 18 min read
#COVID19 #VariantDashboard - #UnitedStates

TOP lineages (#15DAYTRENDS):

60.7% XBB.1.5
7.3% XBB.1.16👀
4.1% XBB.1.9.1
1.3% XBB.1.5.1
1.3% XBB.1.9.2
1.2% XBB.1.5.19
1.1% XBB.1.16.1👀
1.0% XBB.1.5.31

#SARSCoV2 Tracker: tinyurl.com/mryj4uu7 Updated: 04/19/23
1/n Image Use "Airport Surveillance" (AS) pull-down menu to easily track variant proportions Nationally or by State with or without AS sequences

Top lineages (#15DayTrends w/o AS seqs):

XBB.1.5 (65.9%),
XBB.1.9.1 (4.2%),
XBB.1.16 (3.4%),⬆️👀
XBB.1.5.19 (1.4%),
XBB.1.5.1 (1.3%)

2/n Image