Riya Sam, MD Profile picture
#ACCFIT @UCNSCards • Former Chief Resident • ABIM certified • ACC Mentee • Board game geek • Bibliophile📚 • Malayali 🇮🇳 from 🇴🇲 • Jer 29:11 ✝️
Nov 15, 2023 40 tweets 5 min read
#AHA23 LBCTs one liners:

1. SELECT: Among patients w/ overweight or obesity + established CVD w/o DM once-weekly SQ SEMAGLUTIDE was associated with a decreased risk of MACE comprised of CV death, nonfatal MI, and stroke compared with placebo 2.DAPA-MI: Among patients with acute MI w/o a hx of DM or c/c HF, DAPAGLIFLOZIN has better cardiometabolic outcomes compared with placebo, with no difference in CV outcomes.
Aug 28, 2023 26 tweets 4 min read
#ESCCongress #ESC2023 LBCTs one-liners:

1. STEP HFpEF: Semaglutide improves HF related symptoms & physical function and greater weight loss compared to placebo in pts w/ HFpEF & obesity 2. COP-AF: Colchine doesn’t significantly reduce preoperative AF/ myocardial injury after non cardiac surgery(MINS) in pts undergoing major non cardiac surgery
Mar 7, 2023 35 tweets 9 min read
#ACC23 #WCCardio LBCT one-liners:

1. CLEAR Outcomes: Bempedoic acid improves long-term CV outcomes and effectively reduces LDL-C compared with placebo among patients with either established ASCVD or those who have a high risk and w/ intolerance to statin therapy 2. TRILUMINATE Pivotal: Tricuspid TEER was safe for patients with severe TR, reduced the severity and was associated w/ an improvement in QOL

3. HALO: Baxdrostat at the doses studied did not significantly reduce SBP/DBP compared with placebo among patients with uncontrolled HTN
Nov 7, 2022 27 tweets 7 min read
#AHA22 LBCTs one liners:

1. TRANSFORM-HF: Torsemide was not superior to furosemide in improving survival among patients treated for decompensated HF.

2. DCP: No differences in cardiovascular outcomes between chlorthalidone and HCTZ among elderly veterans with HTN. 3. PROMINENT: Pemafibrate did not improve cardiovascular outcomes among patients with diabetes and hypertriglyceridemia.

4. IRONMAN: Iron (ferric derisomaltose) infusion is not superior to usual care among patients with HF and iron deficiency.
Apr 5, 2022 13 tweets 5 min read
#ACC22 LBTs/ Featured Research one liners:

1. VALOR HCM: MAVACAMTEN at 16 weeks in symptomatic HCM decreased the need of SRT

2. Sodium HF: in HF outpatients low-Na diet of 1500 mg/day was not associated with a reduction in CV events but moderate benefit on QoL by KCCQ 3. CHAP: In pregnant women with mild chronic HTN, antihypertensives targeted to a BP <140/90 reduced the incidence of adverse pregnancy outcomes

4. POISE 3: In patients undergoing non cardiac surgery, TRANEXAMIC ACID reduced the risk of bleeding ( non inferiority not met)