Robyn Wright Profile picture
β€’ Microbial ecologist (human microbiome/plastisphere) β€’ Postdoc @DalhousieU πŸ‡¨πŸ‡¦ β€’ @WarwickLifeSci PhD πŸ‡¬πŸ‡§πŸ‡ͺπŸ‡Ί β€’ πŸΆπŸ“·πŸŒŠπŸƒβ€β™€οΈπŸš² β€’ she/her β€’
Apr 28, 2022 β€’ 11 tweets β€’ 3 min read
Q: Which is better for taxonomic classification of #metagenomics samples - Kraken2 or MetaPhlAn 3?

A: It really depends!

Read the very short story in this thread, or the full story in my preprint w/ @BetaScience and AndrΓ© Comeau: bit.ly/3EWkYJf

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Now, you may be thinking "but aren't there loads of studies that compare different metagenomic taxonomic classifiers already?" (& you would be right), but what they don't do is compare the impact of different parameters and reference databases on the classifications.

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