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Robyn Wright
@RobynJWright
β’ Microbial ecologist (human microbiome/plastisphere) β’ Postdoc @DalhousieU π¨π¦ β’ @WarwickLifeSci PhD π¬π§πͺπΊ β’ πΆπ·ππββοΈπ² β’ she/her β’
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Apr 28, 2022
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11 tweets
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3 min read
Q: Which is better for taxonomic classification of
#metagenomics
samples - Kraken2 or MetaPhlAn 3?
A: It really depends!
Read the very short story in this thread, or the full story in my preprint w/
@BetaScience
and AndrΓ© Comeau:
bit.ly/3EWkYJf
1/
Now, you may be thinking "but aren't there loads of studies that compare different metagenomic taxonomic classifiers already?" (& you would be right), but what they don't do is compare the impact of different parameters and reference databases on the classifications.
2/