@yaransarkis @MondayNightIBD @MN_GIMD @JosephHabibi_MD @DCharabaty @AllonKahn @drsusankais @AdvaniRashmiMD @DVinsard @SanjeevaniTomar @BassiMehak @GroverDheera @dunleavy_katie @LindaNguyenMD @LinChangMD @JPAchkarMD @SultanMahmoodMD @ReenaKhanna159 @rajVuppaLanchi @BilalMohammadMD @HaniShamseddeen @MvenuGI @gastrodocmattar @moss_md @IBD_Afzali @JJFordeMD 7/ UC:
💥Categories of disease extent :
📍Proctitis: within 18cm of anal verge, distal 2 rectosigmoid junction
📍L-sided colitis:from sigmoid 2 splenic flexure
📍Extensive colitis: beyond splenic flexure @yaransarkis @MondayNightIBD @MN_GIMD @JosephHabibi_MD @DCharabaty @AllonKahn @drsusankais @AdvaniRashmiMD @DVinsard @SanjeevaniTomar @BassiMehak @GroverDheera @dunleavy_katie @LindaNguyenMD @LinChangMD @JPAchkarMD @SultanMahmoodMD @ReenaKhanna159 @rajVuppaLanchi @BilalMohammadMD @HaniShamseddeen @MvenuGI @gastrodocmattar @moss_md @IBD_Afzali @JJFordeMD @AdamEhrlichMD @JBrandlerMD @StonyBrookGI @KU_GIHep @AmyOxentenkoMD @IBDimmunology @Badr_AlBawardy 8/ACG UC Activity Index:
🔥Incorporate both PROs and laboratory- and endoscopy-based values
🔥ESR-CRP: Not specific BUT correlate w/ endo severity of disease; prognostic significance/predicting risk of needing ✂️
🔥Fecal Calpro: Gut specific

@JosephHabibi_MD @MondayNightIBD @KanikaGargMD @JHaydek @MarcelYibirin @GroverDheera @purnie_mae @dunleavy_katie @yaransarkis @ayshaslam999 @jalpa_devi @AmCollegeGastro @AmerGastroAssn @CLindenmeyerMD @doctornikkid @ShimaghavimiMD @IbdClub @ESCCO_Society @IBD_Nutrition @IBDBen @IBD_FloMD @IBDMD @ibdlearn @IBDConference @IBD_Afzali @AsanIbd @PREDICTIBD @ShomronH @BenClickMD @NadeenSarsour @bsc_endoscopy @Bjorn_Rembacken @EndoscopyNow @EndoscopyOthman @UpdatesIbd @PittGILiverNutr @AdvaniRashmiMD @nljonassaint @SyedGerdezi @wabillin @ACGCRJ @drkeithsiau @DrKohli @IFFGD @LinChangMD @vibhuc7 @SLUgastro @priyakathpalia @IBDdoc_BattatMd @APandT 10/How do you maintain remission after successful induction?
✅If pt achieves remission w/ IFX ↔️Maintain w/ IFX, 🔎consider adding AZA to ❌ antibodies to IFX

✅If pts achieve remission w/ IV CysA ↔️Maintain w/ AZA or Vedolizumab @JosephHabibi_MD @MondayNightIBD @KanikaGargMD @JHaydek @MarcelYibirin @GroverDheera @purnie_mae @dunleavy_katie @yaransarkis @ayshaslam999 @jalpa_devi @AmCollegeGastro @AmerGastroAssn @CLindenmeyerMD @doctornikkid @ShimaghavimiMD @IbdClub @ESCCO_Society @IBD_Nutrition @IBDBen @IBD_FloMD @IBDMD @ibdlearn @IBDConference @IBD_Afzali @AsanIbd @PREDICTIBD @ShomronH @BenClickMD @NadeenSarsour @bsc_endoscopy @Bjorn_Rembacken @EndoscopyNow @EndoscopyOthman @UpdatesIbd @PittGILiverNutr @AdvaniRashmiMD @nljonassaint @SyedGerdezi @wabillin @ACGCRJ @drkeithsiau @DrKohli @IFFGD @LinChangMD @vibhuc7 @SLUgastro @priyakathpalia @IBDdoc_BattatMd @APandT 11/ ‼️Potential Role of #TOFA in #ASUC
🔺Pts had Failed >= 2 biologics; PO prednisone
🔺TOFA 10mg po TID ➡️ Rapid symptom improvement + ⬇️CRP
🔺F/U:
TOFA maintenance
❌✂️ at 30 D & 90 D
❌Readmissions at 90 D
2/4 pts ➡️ clinical + endo steroid-free remission
❌Major AEs