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Avinash Rao Ullur, MD DNB FASN AHSCP-CHS Profile picture
Avinash Rao Ullur, MD DNB FASN AHSCP-CHS
@TheBeaniac
Clinical Fellow👔 in Onco-Nephrology @UofT, #NSMC 2021🎓, #WCN SoMe member, @onconephsociety SoMe member, #ASDIN SoMe member
Mar 30, 2021 • 14 tweets • 6 min read
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🎤“Don’t make a change too complicated, just begin.”

🔊 We have a chance to make a ‘change for good’ in anemia Rx in CKD.

👥Let’s discuss hypoxia-inducible factor prolyl hydroxylase inhibitors (HIF-PHIs), the probable champions🏆 of NephMadness 2021. #AnemiaRegion 2/ 📖Hypoxia Inducible Factor (HIF) - Physiology

- Present in all tissues.
- Has O2 regulated 𝞪 (3 isoforms) and constitutively expressed 𝛃 subunits.
- HIF-2𝞪 is expressed in the peritubular fibroblasts, mainly involved in the upregulation of EPO gene.
Mar 12, 2021 • 12 tweets • 7 min read
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It has been more than a century tackling Anemia in CKD since its first description by Richard Bright in 1835.

👉 #NephMadness 2021 is featuring strong contenders from the #AnemiaRegion.

🤔 Let's find out why Anemia in CKD is an important consideration. #NSMCInternship 2/📊 What % of patients with CKD stage 4 have anemia based on KDOQI (Hb <13.5 g/dL for men and <12.0 g/dL for women) and WHO (<13.0 g/dL for men & <12.0 g/dL for women)?