- Present in all tissues.
- Has O2 regulated 𝞪 (3 isoforms) and constitutively expressed 𝛃 subunits.
- HIF-2𝞪 is expressed in the peritubular fibroblasts, mainly involved in the upregulation of EPO gene.
Mar 12, 2021 • 12 tweets • 7 min read
1/12
It has been more than a century tackling Anemia in CKD since its first description by Richard Bright in 1835.
🤔 Let's find out why Anemia in CKD is an important consideration. #NSMCInternship
2/📊 What % of patients with CKD stage 4 have anemia based on KDOQI (Hb <13.5 g/dL for men and <12.0 g/dL for women) and WHO (<13.0 g/dL for men & <12.0 g/dL for women)?