Hypothermia not superior to normothermia in OHCA for patients sill comatose. #paperinapic by the talented @KirstyChallen #FOAMed #EBM
thesgem.com/2021/07/sgem33…
@NEJM @RCEMLearning @stemlyns thesgem.com/2021/07/sgem33…

Patient has ROSC after OHCA but is comatose. What's your target temperature in the ED? #EBM #FOAMed thesgem.com/2021/07/sgem33… @First10EM @emcrit @NEJM @ACEPNow @srrezaie @stemlyns The 5 Step Process:
1-Vote on the twitter poll
2-Retweet the twitter poll
3-Read the primary pub (TTM2 trial) nejm.org/doi/full/10.10…
4-Check out the TheSGEM.com appraisal
5-Earn your CME credits sgem.ccme.org

This is a reason why there is a lack of consensus on lytics for #stroke:
- 13 foundational RCTs
- 4 stopped early for harm or futility
- 8 of 13 used tPA
- Only 2 reported benefit for primary outcome
- Neither were replicated
-Both reanalyzed & failed to confirm benefit. This lack of consistent evidence for potential benefit combined with the evidence of increase for potential harm (ICH&death) is a reason we (@First10EM) downgraded the NNT recommendation to yellow. It highlights the uncertainty of the existing evidence. thennt.com/nnt/tissue-pla…

The fragility of stroke thrombolysis.

tasmanmedicaljournal.com/2020/01/the-fr…

@CAEP_Docs @ACEPNow @acemonline @CAEP_Docs @ACEPNow @acemonline @EddyLang1 @mihill68 @noreenkamal @Rick_Pescatore @EMSwami @EMNerd_ @PulmCrit @srrezaie @SAEMEBM @stemlyns When reviewing SRMA we should consider conflicts of interest. Emberson et al reported multiple COI while the Donaldson et al reproted none.
@JeanneLenzer1