👨💻 intersection of machine learning and biology. Research Engineer and Manager at Fundamental AI Research (FAIR) @MetaAI. Previously NYU, IBM Research.
Dec 22, 2022 • 7 tweets • 5 min read
Language models understand natural proteins. But can they generalize beyond, to design completely new proteins from scratch?
New preprint: biorxiv.org/content/10.110…
A 🧵
Today we share the result of a >2 year collaboration w @UWproteindesign & @sokrypton on designing proteins w the ESM2 protein language model. We show that: yes, we can generate de novo proteins using the LM alone.
We experimentally tested 228 proteins with a 67% success rate! 2/
Nov 2, 2022 • 13 tweets • 7 min read
Yesterday we launched the ESM Metagenomic Atlas and ESMFold. We released a lot at the same time, so let me give an overview.
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