A link between HAPE (High-Altitude Pulmonary Edema) and COVID-19 is Aldosterone. Glucocorticoids may help preserve endothelial cell membrane.
"The plasma aldosterone level rose continuously and on the last day of altitude was significantly elevated."
pubmed.ncbi.nlm.nih.gov/6780338/2/ "A possible explanation is that inhaled budesonide, as a glucocorticoid agent, preserved the integrity of pulmonary endothelial cell membrane.."