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Jan Verwerft Profile picture
Jan Verwerft
@VerwerftJan
Cardiologist 🇧🇪 | ExerciseEchocardiography | HeartFailure | ValvularHeartDisease | @JessaZiekenhuis | @hartcentrumh
Jun 15 • 15 tweets • 4 min read
Check out our latest 📄 🇧🇪🇨🇦🇦🇺

The Oxygen Cascade According to HFpEF Likelihood: A Focus on Sex Differences | JACC: Advances



Regardless of #HFpEF probability scores, ♀ have ⬇️peak VO2 than ♂ ⏪ ⬇️ O2 delivery &⬇️ O2 extraction

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Background: bit.ly/4epUf9q
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Method: combined CPET and #ExerciseEchocardiography in a dyspnea clinic
no EF < 50%, no history of HF, no more than mild pulmonary disease and valvular heart disease
Feb 9, 2022 • 14 tweets • 36 min read
Excited to share our paper with @AndreasGevaert and @FH_Verbrugge @HartcentrumH @HerbotsLieven @guido_claessen @PaulDendale
doi.org/10.3389/fcvm.2…
We know that systolic reserve is reduced in #HFpEF; but can systolic reserve help in the diagnosis🤔? 22 pts with simultaneous #iCPET and #ExerciseEchocardiography: Elevated
exPAWP (≥25 mmHg = elevate LVFP) was present in 14 patients, and was best identified by peak septal systolic annular velocity <9.5 cm/s (exS’) with an AUC of 0.97