professor at UCSF, engineer turned cell biologist, wants to know how cells solve geometry problems
Feb 13 • 11 tweets • 3 min read
When you work with biological molecules, warmth is the enemy. Whether it's antibodies, proteins that you have purified from cells, or all of the enzymes that make molecular biology and gene cloning possible, unless you keep them very cold, they will rapidly become useless.
because of this, every biomedical research lab has lots and lots of freezers and refrigerators. The freezers aren’t like ones in your kitchen because those aren’t cold enough to keep proteins intact. Instead we use -80° freezers. Every lab has at least one, often more
Sep 30, 2022 • 23 tweets • 7 min read
Very happy to announce our new preprint from Karina Perlaza and Ivan Zamora in which we tried to understand how transcription is regulated during flagellar regeneration in Chlamydomonas and found that IFT has an unexpected (by us) role biorxiv.org/content/10.110…
This paper is part of our long-term project to use flagellar length control in Chlamydomonas to understand the general question of organelle size control. An important aspect in organelle size is regulation of the building blocks, and that's what this paper addresses