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Armin Töpfer Profile picture
Armin Töpfer
@XLR
Husband. Parent. Dr sc @ETH. Bioinformagician. Father of @PacBio HiFi. C++ Purist. Geek. Digital Artist. Electronic music. Speaks in memes. Opinions are my own!
Oct 26, 2022 • 16 tweets • 7 min read
Have you heard about Revio by @PacBio at #ASHG22? It is such an amazing platform, 4x30-fold HiFi human genomes every 24 hours. Let me show you what it took to get this bioinformatics performance on the instrument. A thread on CCS GPU acceleration and DeepConsensus productization. Image The team behind CCS has been working hard for the past years to reduce runtime massively for the initial SQIIe and subsequent releases. We pulled all tricks to get the CPU code as fast as possible, but Revio is a completely different beast. Generating 90Gb HiFi per SMRT Cell 25M! Image