Former EMBO Postdoctoral Fellow in the Baker Lab at @UWproteindesign. Interested in developing new generative ML methods for designing proteins. Views my own.
Dec 1, 2022 • 14 tweets • 8 min read
DALL-E’s amazing images are popping up all over the web. That software uses something called a diffusion model, which is trained to remove noise from static until a clear picture is formed.
Turns out diffusion models can design proteins too!
Today we’re sharing a deep-learning method for protein design called RoseTTAFold Diffusion. With minimal input, it turns prompts (“create a molecule that binds X”) into new proteins that fold and function in the lab. We’ve tested 100s already.
