Assistant Professor at University of Graz in Austria. Used as a work account for discussing my research & related topics. 🐘 @adam_t_clark@ecoevo.social.
May 14 • 14 tweets • 4 min read
I usually love reporting from @ryangrim. I think this piece does a really good job of highlighting the lack of reporting around COVID vaccine side-effects, but misses very important context on differences between AstraZeneca and other vaccine types. 1/n
For context, I'm not a rosey-eyed vaccine optimist: here is me in April 2021 going through early cost/benefit data on AstraZenca and suggesting that young folks should consider refusing it (I myself waited for Pfizer based on this and follow-up data): 2/n
I was disappointed by the news conference today from the EMA regarding #AstraZeneca. The upshot is that AZ has been tied to rare cerebral thrombosis, but EMA still believes that benefits outweigh the costs (on average). 1/n ema.europa.eu/en/news/astraz…
But, I am worried that we are going to have to eventually pay back the balance on three issues that have been largely pushed under the rug, but risk undermining public trust and slowing down vaccination campaigns in the the EU and worldwide: efficacy, risk, and side effects. 2/n
Feb 22, 2021 • 18 tweets • 5 min read
I don't was to get too far from my tree, but there's a growing issue at the stats/policy boundary regarding #AstraZeneka and #B1351 that I wish was getting more series coverage. The EU needs lots of people (20-30%?) to agree to be vaccinated with AZ, but many don't want to. 1/n
Reasons include lots of things that aren't well supported by data (e.g. "higher side-effects", "slower efficacy"), but also some that are, especially regarding very low efficacy against mild to moderate cases of the B.1.351 "South African" variant. 2/n
There's been a lot of media buzz around the efficacy of the AstraZeneca vaccine against the B.1.351 COVID-19 Variant first identified in South Africa. In particular, a recent study by @ShabirMadh et al. suggests it could be very low, at least for mild to moderate cases. 1/25
I've seen lots of people suggest that the sample sizes in the study are "too low" to say anything definitive - but, this is actually a pretty good opportunity for a power analysis. Since I haven't seen much discussion of the study's power, I thought I would post one here. 2/25
