(he/him) Principal Investigator at @CeMM_News;
Computational Biology of Aging and Pathology; afrendeiro@sciencemastodon.com;
afrendeiro@bsky.social
Nov 16 • 9 tweets • 4 min read
What if we could look at a human tissue image🔬and quantify its biological age?🧬 And how could we get the same insights without collecting a tissue sample?
In our new @biorxivpreprint, we create "tissue clocks" ⏳to do just that!
📝
#aging #tissue 🧵below biorxiv.org/content/10.110…
For many human tissues it is not known how molecular and cellular aging changes lead to the decline of physiological function. This work is a step towards the systematic quantification of the aging process structrurally in human tissues at scale.
Dec 19, 2019 • 12 tweets • 6 min read
Very excited to share our new preprint describing a method for ultra-high throughput single-cell RNA-seq biorxiv.org/content/10.110…#scRNAseq
Our new method (scifi-RNA-seq) uses a mixture of plate-based combinatorial and droplet-based fluidic indexing to achieve an unprecedented balance of ease-of-use and throughput in a single experiment.