1/5
I'm a cardiologist. I'm 58 years old. I was born in Iran, exiled as a child, and rebuilt my life from nothing in a country that owed me nothing.
It took me decades to understand what I'm about to tell you.
I learned some of these lessons in medical school. Some in the cath lab at 3 AM. Some from Rumi and Rabbi Nachman. Some from patients who taught me more about living in their final hours than I learned in four years of residency.
I wish someone had given me these words at twenty. No one did. So I'm giving them to you now. 2/5
The less you say, the more your words carry. I've spent thousands of hours in ICU waiting rooms. The person everyone turns to is never the one who talked most. They're the one who waited, listened, and spoke only when it mattered. Silence isn't emptiness. It's precision. The Kotzker Rebbe said: not everything that is thought should be said. Not everything said should be written. Not everything written should be published.
Don't take everything personally. Most people are far too consumed by their own fears and insecurities to think about you as much as you imagine. I spent years believing the world was scrutinizing my every misstep. It wasn't. It was busy with its own. The freedom that comes from truly understanding this is one of the most underrated gifts of getting older.
What you focus on becomes your reality. The Kabbalists mapped this centuries ago — where your attention goes, your life follows. I've watched patients with terrible prognoses outlive patients with better numbers, because one group focused on what they could still build and the other focused on the verdict. Your mind is not a passenger in your life. It's the steering wheel.

1/5
I'm a cardiologist. I'm also an Iranian Jew.
I don't talk about this often on here. But today I want to tell you something about who I am — and why I see the world the way I do.
My family's roots in Persia stretch back roughly 2,700 years. We were among the oldest continuous Jewish communities on earth. Synagogues in Isfahan. Scholars in Shiraz. Merchants and physicians in Tehran. We survived every empire that rose and fell across that ancient land.
And then, in a single generation, most of it vanished.
After 1979, the Jewish community of Iran — once 100,000 strong — collapsed. My family was among those who left. We carried our faith, our language, our poetry, our medical traditions, and the memory of a home that no longer wanted us.
We came to America. 2/5
I love this country with a depth I think only immigrants fully understand.
Not the abstract love of someone born into abundance. The fierce, protective, almost desperate love of someone who has seen what happens when the foundations that guarantee liberty shift beneath your feet.
America gave my family something Persia could not: the freedom to build without fear. The freedom to practice medicine. To pray openly. To raise children in safety. To write, to speak, to dream — without looking over our shoulders.
Every opportunity I've had — UCLA, my cardiology practice, my books, this platform — exists because America kept its promise to a family that arrived with almost nothing.
That kind of debt doesn't expire. And that kind of gratitude doesn't stay quiet when you feel the foundations being tested.

1/5 I'm a cardiologist. After twenty years of treating hearts, I've arrived at a truth that changed how I practice medicine.
The health of your brain is inseparable from the health of your heart. They rise or fall together.
And cognitive decline doesn't begin the day you forget a name or misplace your keys.
It begins years earlier — the moment movement quietly disappears from your daily life.
This isn't a metaphor. It's a biological mechanism. And once you understand it, you'll never think about sitting the same way again. 2/5
Your brain is the most adaptive organ in your body. It constantly scans for demand.
When you sit for hours — at a desk, in a car, on a couch — your nervous system receives a very clear message: demand is low. The body isn't moving. The brain reasons it doesn't need to maintain full processing power.
So it begins to dial things down.
Neuroplasticity decreases. BDNF — the brain's natural growth fertilizer — drops. Neural connections get pruned. The hippocampus, prefrontal cortex, and other regions governing memory, focus, and decision-making slowly shrink.
Here's the insight that changes everything: your brain isn't breaking down from damage.
It's adapting. Rationally. To reduced demand.
The same way a muscle atrophies when it isn't loaded, your brain withdraws investment when it isn't challenged by physical movement. And the adaptation happens terrifyingly fast — a few weeks of prolonged sitting can shift the trajectory.

1/5
.@elonmusk just told Forbes: "The future of medicine will be digital. If you know what to program into that synthetic RNA strand, you can basically cure anything."
The internet is divided. Half think it's visionary. Half think it's hype.
I'm a cardiologist. I already prescribe RNA-based medicine to my patients. In my office. Today.
Let me show you exactly where we are — what's already real, what's coming, and what's still theoretical. No hype. No fear. Just the clinical truth. 2/5
What's already here — right now, in my practice:
Inclisiran. Brand name Leqvio. An siRNA injection I administer to patients twice a year. It silences the PCSK9 gene in the liver — the gene responsible for producing a protein that raises LDL cholesterol.
Two shots a year. LDL drops roughly 50%. No daily pills. No monthly injections. The drug enters your liver cells, finds the specific mRNA that codes for PCSK9, and destroys it. Your liver simply stops making the protein that was raising your cholesterol.
FDA-approved. Now cleared as first-line monotherapy as of last year. Sustained LDL reduction documented out to nearly 7 years. Over 60,000 patients across 30+ clinical trials.
That's not digital medicine as a metaphor. That's literally a synthetic RNA strand programmed to silence one gene. Musk's language is engineering shorthand for what I already do in clinic.

1/5
I'm a cardiologist. Here's why I recommend men take 5 mg of tadalafil — Cialis — every single day.
Not for ED. Not for performance.
I take it for the same reason every serious longevity physician I respect does: to protect my cardiovascular system, my brain perfusion, and my endothelial health at the most fundamental level.
This drug — famous for all the wrong reasons — has quietly become one of the most powerful tools in preventive cardiology. And the data is now too strong for me to keep quiet about it. 2/5
Here's what tadalafil actually does.
PDE5 is the enzyme that breaks down cGMP — the molecule that tells your smooth muscle to relax and your blood vessels to dilate. By blocking PDE5, tadalafil produces system-wide vasodilation: better blood flow to the heart, brain, lungs, kidneys, muscles — every organ downstream of your vascular tree.
Unlike Viagra, which lasts 4-6 hours, tadalafil's effects last up to 36 hours. A low daily dose keeps plasma levels stable around the clock.
Now here's why this matters for your heart.
Endothelial dysfunction — the failure of that thin layer of cells lining 60,000 miles of your blood vessels — is the earliest, most predictive marker of cardiovascular disease. It precedes plaque, heart attacks, and strokes by years. By the time most patients reach my office, the damage is done.
Tadalafil directly improves endothelial function. It reduces arterial stiffness. It shows anti-fibrotic effects on the heart muscle in preclinical models. It's already FDA-approved for pulmonary arterial hypertension.
Most patients come to me when something has already broken. I'm treating the pipes before they clog.

1/5
I'm a cardiologist. I have spent twenty years watching cholesterol destroy arteries, trigger heart attacks, and kill people I care about.
Today, Eli Lilly presented data that may begin to end that era.
VERVE-102. A single infusion. One dose. It uses base editing to permanently turn off the PCSK9 gene in your liver.
Presented today at the European Atherosclerosis Society Congress:
88% reduction in PCSK9.
62% reduction in LDL cholesterol.
Sustained up to 18 months.
No treatment-related serious adverse events.
One infusion. Not daily pills you forget to take. Not monthly injections. One dose — and your cholesterol may stay low for the rest of your life. 2/5
Let me explain why this is so profound.
There are rare people born with naturally occurring loss-of-function variants in the PCSK9 gene. Their bodies produce very little PCSK9 protein. Their LDL cholesterol stays naturally low throughout their entire lives. They almost never develop coronary heart disease.
VERVE-102 is designed to give that same genetic protection to anyone who needs it. One infusion. Permanently edits the gene. Mimics what nature already does in the luckiest among us.
Lilly acquired the technology for roughly $1 billion and is preparing to launch Phase 2 trials by the end of this year.
Heart disease remains the number one killer on earth. Every moment of LDL exposure matters for your lifetime cardiovascular risk. A one-time treatment that durably eliminates excess LDL could prevent millions of heart attacks that haven't happened yet.
This is not incremental. This is a paradigm shift.

1/5
I'm a cardiologist. I need to tell you something that will change how you think about heart disease screening.
The standard approach — EKGs, echocardiograms, stress tests, basic labs, a cholesterol panel — misses approximately 75% of people who will go on to have a heart attack, stroke, or cardiac death.
These tests check how your heart functions. They do not check what's quietly building inside your arteries.
And the arteries are where plaque accumulates silently for decades before you feel the first chest pain. By then, the event is already happening.
Most heart attacks aren't caused by severely blocked arteries. They're caused by soft, inflamed, rupture-prone plaque that no stress test on earth will detect.
There is a better way. I use it in my practice. Here are the tests that actually find the disease before it finds you. 2/5
Coronary CT Angiogram with AI plaque composition analysis.
This is the single most important upgrade in cardiac prevention in the last decade.
It visualizes your coronary arteries in 3D, quantifies your total plaque burden, and — critically — uses AI to tell me exactly how much plaque is soft, lipid-rich, and rupture-prone versus stable and calcified.
Why this matters: non-obstructive plaque causes most cardiac events. Your arteries can look "clear enough" on a stress test while harboring the exact kind of soft plaque that ruptures without warning. This test finds it.
Medicare just started reimbursing AI-enhanced plaque analysis. If you're over 40 with any risk factors, ask for this by name: coronary CT angiogram with plaque composition analysis.
If soft plaque is found early, we can stabilize and often reverse it with aggressive statins, PCSK9 inhibitors, GLP-1s, and lifestyle intervention. I've seen it happen in my practice.

1/5
I need to talk to you about what GLP-1 drugs are doing to the brain.
For decades, medicine has treated metabolic health, cardiovascular health, and mental health as completely separate systems. Separate doctors. Separate drugs. Separate departments.
Biology may not work that way.
A landmark study just published in The Lancet Psychiatry is forcing us to reconsider everything. 2/5
Taipale et al. tracked 95,490 people across 13 years of Swedish national data — people with pre-existing depression and anxiety, compared against themselves on and off semaglutide.
44% less worsening depression. 38% less worsening anxiety. 47% less worsening substance use disorder. 44% less self-harm.
Nearly half. Across every psychiatric measure they tracked.
"Ozempic personality" dominated headlines recently — the fear that GLP-1 drugs flatten your ability to feel pleasure.
But if semaglutide stole pleasure at scale, depression would climb.
It fell by nearly half.

1/5
I'm a cardiologist. I hear this in my office constantly:
"But my annual labs were always normal."
They're telling the truth. Their labs were normal.
But the standard blood panel has a fatal flaw — it was designed to find disease that's already there.
We wait for the house to catch fire. Then we try to put it out.
There are 8 tests that detect the frayed wiring years before the first spark. Most cost under $50. None are experimental. And they are completely missing from your annual physical. 2/5
Lipoprotein(a) — Lp(a).
This is 100% genetic. You can run marathons. Eat perfectly. Still have sky-high levels. 1 in 5 Americans are elevated, which triples heart attack risk.
You only need to check it once in your life because your levels are set at birth. The 2026 ACC/AHA guidelines now recommend everyone be tested.
Most people never have been.
Apolipoprotein B — ApoB.
For decades we've obsessed over LDL cholesterol. But LDL measures the cholesterol inside the particles. ApoB counts every single particle crashing into your artery walls.
A 2024 analysis found that 54% of patients had dangerous ApoB levels that standard LDL testing missed entirely. If you're only looking at LDL, you're driving with one eye closed.

I'm a cardiologist. I take 7 supplements every single day.
Walk into any pharmacy and you'll see a hundred bottles promising miracles. Most are marketing. Some are actively harmful.
But a small few actually work — backed by real science, confirmed in my own practice, and taken by me personally every morning and every night.
Here's the honest list. 2/5
Creatine — 5g in water every morning.
Most people think this is for gym bros. It's not. It helps every cell in your body produce energy more efficiently — including your heart muscle.
Stronger muscles as you age. Faster recovery. Sharper thinking. A heart that doesn't tire as easily.

The world just witnessed the impossible. In exactly twenty-eight days, President Trump didn’t just win—he executed the most surgical, brilliant, and devastating military masterclass the modern West has ever seen. The IRGC has gone from a regional threat to total structural collapse.

​No endless war. No American blood spilled in the sand. No trillion-dollar quagmire.

​This wasn’t just a victory; it was the birth of a new era. Here is how the Trump Doctrine redefined global power in one month:

​⚡ THE CYBER BLACKOUT: "THE MASTERSTROKE"
​When the Mullahs broke the ceasefire, Trump didn’t just drop bombs—he dropped the lights. In a display of absolute cyber supremacy, U.S. forces hacked the regime’s command-and-control infrastructure. Overnight, their military communications went silent and their power plants went dark. The IRGC was paralyzed before a single tank could move.

​🛡️ ECONOMIC SHIELD & ENERGY VICTORY
​While critics predicted a global recession, Trump protected your wallet. He moved with lightning speed to secure the Strait of Hormuz, forcing it open and ending the threat to global shipping. The result? Market panic evaporated, 401ks remained stable, and oil prices crashed—delivering instant, massive relief at the pump for every American family.

​💰 THE SELF-FUNDED OPERATION
​In the ultimate "Art of the Deal" move, Trump seized Kharg Island—the crown jewel of Iran’s oil empire. Instead of asking American taxpayers to foot the bill, he used the enemy’s own oil resources to fund the operation. Zero cost to the American people. Maximum cost to the tyrants.

​🔥 THE END OF THE TERROR MACHINE
​The IRGC's ability to fund Hamas, Hezbollah, and the Houthis has been systematically dismantled. Their missile fleets are scrap metal. Their "Iron Fist" is shattered. By cutting off the head of the snake, Trump has drained the swamp of Middle Eastern terror once and for all.

​THE MOST BEAUTIFUL PART?
With the terror machine broken and the Mullahs in hiding, the brave people of Iran are rising. They smell freedom. They see a future without fear. The nightmare for the regime is just beginning, and the dawn of a free Iran is finally within reach.
​The Trump Doctrine is clear:
​Maximum Pressure
​Minimum Force
​Zero Nation-Building

​The IRGC lost their empire of terror. The world gained peace. Tyrants now know the rule of the game: Play stupid games, win devastating prizes.
​Freedom just roared back to life. 🦅
Trump delivered. The world won.
​#TrumpDoctrine #PeaceThroughStrength #MiddleEast #Freedom #MAGA #AmericaFirst #28Days

https://x.com/i/status/2041856927400128876

While the world watches the Mediterranean, the real move is happening in the silence of the Indian Ocean.

​The Intel:
​6 B-2 Spirits just landed at Diego Garcia. That’s half the entire U.S. stealth fleet.
​Dozens of KC-135 tankers have surged to Qatar since Jan 5th.
​This isn’t a "show of force." It’s the exact logistics pattern that preceded Operation Midnight Hammer.

​The Twist:
Israel is on maximum alert, but not for the reason you think. Three sources confirmed to Reuters: Israel isn’t preparing for an Iranian attack. They are preparing for a U.S. strike on Tehran.

​The Trigger:
Marco Rubio called Netanyahu while 400 bodies were being stacked at Kahrizak. The threshold Trump set—the "red line" of human rights and regional stability—has been crossed ten times over.

​The Sky is Empty:
Qatar, Emirates, Lufthansa... they’ve all pulled out. When commercial aviation clears the airspace, it’s because someone expects ordnance.
​Trump has the options. The bombers are fueled.
What happens next defines the decade.

SOON.

FREE IRAN.
@POTUS @realDonaldTrump
LFG

https://x.com/i/status/2010422605732569228

1. You Are Not the Problem — You Are the Answer
We were not born into perfection that somehow fell apart.
We entered a world designed to need repair — a world yearning for our participation.
You are not here to redeem yourself or prove your worth.
You are here because God trusts you to be part of the healing.

The suffering, the confusion, the brokenness you see — these are not signs of divine failure.
They are the raw materials of redemption, the canvases upon which you are invited to paint light. 2. The Meaning of Suffering
Suffering is not a punishment. It is an invitation.

Each trial — loss, illness, betrayal, loneliness — is a divine compliment.
It is as if God whispers: “I trust you to walk through this darkness and bring light from it.”
The soldier chosen for the hardest mission is not cursed; he is honored.
So too are we, when life’s burdens fall upon us.

Pain is not proof of divine anger — it is proof of divine confidence.

A @UCLA "professor" being schooled by a Jewish student on the definition of "genocide"

These schools are infected by Islamist, Communist, Leftist feelings and emotions of rage based on no logic. 🤦

https://x.com/afshineemrani/status/1783656976897175825

Most Americans have never seen school closures because of Islamist attacks. There are Persians/ Iranians who escaped Iran and walk among you. Ask them how it was. It smells the same. Let me just tell you a few things. It is NOT about Jews. It is NOT about Israel. It is NOT about "Free Palestine!" This is foreign powers trying to bring down America. You MUST understand this. China. Russia. Iran's regime. They see weakness in American leadership and they are trying to topple this country. How? By creating CHAOS where people are most vulnerable. Our top schools. That's how it started in Iran. "Intellectuals" thinking they are standing up for a cause- for human rights, all the while being manipulated by paid actors. Communists. Islamists. Socialists. Propelled by social media. TikTok. Instagram. Meta. And now, illegal immigrants who have nothing to do and those who love to see destruction, like from Pakistan. Unfortunately, this will get a lot worse until after our elections. The foreign powers want to ensure America never becomes great again and stays engaged fighting multiple proxie wars all over the world, while China gets ready to swallow Taiwan. What is the anwser? 1- We must understand what is happening. Read this and talk to your Persian friends who escaped the Revolution of 1979. I'm sorry to say, but we have been warning you and we understand things you just don't. 2- We must all stick together. Do not allow them to divide us. We must stay strong against these barbaric acts on campuses. They have no room there. We respect all people- Muslim, Jews, Christians, and all people, but there must be no encampments and no violence and no blocking students from going to classes, and no threatening any groups or teachers. These incompetent presidents must be fired! 3- The police and the National Guard should be brought in to clean up campuses so our children can get back to school. 4- Be vigilant. Report criminal activity. Law enforcement must be alerted over and over again. 5- We need to DEFUND the defund-the-police movement. We need our cops! We need our police. Talk to them. let them know you appreciate them. Give to your local police. 6- Vote RED! The entire world needs to move away from woke agenda, radical Leftist ideology and move to the Right which at this point is the center. 7- Do NOT stay silent. Speak up. These bullies feed on those who remain quiet. Show them they are NOT welcome and will not be tolerated. 8- Stay positive. WE WILL WIN! I promise you, this is the end of the madness that started with the pandemic. Next year things will get much much better- but until then, God bless America and all that is right with this beautiful country.

https://x.com/MosabHasanYOSEF/status/1782796325941330340

Some people rushed to remove photos of Israelis hostages taken by Hamas terrorists. So someone in Los Angeles decided to light up buildings with their photos. We will never give up. #bringthemhome #StandWithIsrael #HamasTerrorist
#AmYsraelChai

https://x.com/AvivaKlompas/status/1714266953630802037?s=20

Mom shares heartfelt message about her daughter who wanted to be a boy.

PLEASE READ AND RETWEET:

"This is my middle daughter Hope at 3 and 18. When she was about 2.5 yrs old, she told me she wanted to be a boy. This continued in different forms until she was 12-13. She asked me… twitter.com/i/web/status/1… @jordanbpeterson

HUGE NEWS. Reporters are being arrested for reporting on the train derailment in Ohio which experts say is going to be the next Chernobyl! 10% of U.S. population, over 30 MILLION PEOPLE, live in the Ohio River Basin- which provides drinking water to over 5 MILLION PEOPLE!

https://twitter.com/CitizenFreePres/status/1625166530022612993?s=20&t=KqI6YtZwBV8YNxZr2EUmFw

The Bible tells us that Sarah died suddenly. Immediately after Abraham's binding of Isaac. I wonder if this was the first case of Takotsubo cardiomyopathy – known as broken-heart syndrome or stress-induced cardiomyopathy. A mother's grief leading to sudden death. It's real and happens almost always women who experience tremendous stress, particularly domestic violence or significant loss. 2/

Nevada will not be done counting until SATURDAY because they found 67,000 more ballots in local drop boxes. I genuinely want to believe in our voting system. I want to think there is no fraud. But, we need to revamp this entire system. 1/ For both sides of the aisle. Where do we draw the line? Saturday? Sunday? One month? Next year? We need to have IDs. No mail-in ballots. Vote via the internet or phone with quick ID checks. 2/

European doctors sounding alarms about a mysterious increase in deaths. Massive spikes in excess deaths. And they say it's not related to covid. What is going on?

Crisis as excess deaths soar to levels higher than during Covid pandemic telegraph.co.uk/news/2022/11/0… Daily excess death numbers are worse than those during the pandemic.

Don't forget- in addition to getting vaccinated/ boosted- patients couldn’t get to a doctor, get tests, have a biopsy, start chemo... Shame on those who pushed lockdowns!