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Alok Javali Profile picture
Alok Javali
@alok_javali
Postdoc at @IMBA_Vienna; Research interest: Stem cells, Early mammalian development; Stem cell based developmental models
Dec 2, 2021 • 30 tweets • 10 min read
Extremely excited to share our recently published paper in @Nature where we report formation of a faithful in vitro model of human blastocyst. @NRivron lab @IMBA_Vienna
A long tweetorial alert! [1/29]
nature.com/articles/s4158… Right starting cells necessary to form the correct model of blastocyst. We use naive ESCs, cultured in PXGL medium (developed by Austin Smith’s lab), as these are transcriptionally most similar to blastocyst epiblast; have robust potential to form all blastocyst lineages [2/29]