Founder & CEO, GreenLight Biosciences, RNA research, development and manufacturing
Dec 21, 2020 • 15 tweets • 3 min read
Mutations to the Covid-19 virus in the UK are worrying, but not surprising. There are thousands of known mutations to the virus, it was only a matter of time before one changed the rate of infection.
This is why we need to vaccinate the world. Each transmission by infection opens the threat of mutation.
In the worst case scenario, a mutation renders existing vaccines ineffective.
Dec 4, 2020 • 7 tweets • 2 min read
Pfizer scaled back its 2020 RNA vaccine production estimate.
Here’s the 5 challenges from the point of view of an RNA producer. 1. Messenger RNA was only produced in labs until recently. Scaling up needs facilities and inputs. The supply chain is the main challenge.
wsj.com/articles/pfize…
Nov 9, 2020 • 44 tweets • 8 min read
Good news today with results from Pfizer/BionNtec. I thought it would be helpful to sum up what that will mean, particularly with regard to mRNA vaccines such as the one GreenLight is developing. In sum we will need more than one vaccine.
Over the next several months, I hope, we’ll see many different vaccines approved. Loosely speaking, they’ll come in three generations. The first should be licensed in the next several weeks; the second early to mid 2021, and the third batch later.
