Assistant Professor of Biomedical Informatics, Harvard Medical School @HarvardDBMI | Founding Deputy Editor, @NEJM_AI | Co-host, NEJM AI Grand Rounds
May 1 • 16 tweets • 5 min read
🧵1/ Our new study on AI and physician reasoning just came out in @ScienceMagazine. As co-senior author, I'm excited about our findings, and I do think AI will reshape medicine. But after seeing some of the discussions, I'm also worried about how our findings may be misinterpreted.2/ First, a huge shoutout to our superstar co-first authors @PeterBrodeurMD (IM resident @BIDMC_IM) and @tabuckley_ (PhD student in @AIM_Harvard_PhD). Without them this paper would not exist.
Apr 10, 2019 • 9 tweets • 5 min read
(Thread) 2019 problem: you have a big dataset and everything is significant after Bonferroni. What's spurious; what's real? How do you prioritize? Happy to share my take w/ John Ioannidis & @chiragjp out now in the American Journal of Epidemiology: academic.oup.com/aje/advance-ar…
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Some background: Inspired by Genome Wide Association Studies (GWASs), 'X-WASs' have emerged as systematic, agnostic, and reproducible approaches to discovery with non-genetic data (e.g. X = Environment, Medication, Phenotypes...etc.) For ex., the EWAS by @chiragjp et al. 2/n