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Omer Ali Bayraktar Profile picture
Omer Ali Bayraktar
@bayraktar_lab
Group leader at @sangerinstitute Neural diversity, spatial transcriptomics, glia, GBM https://t.co/AGAGRUasuI…
Nov 18, 2020 • 10 tweets • 7 min read
Proud of our 1st manuscript! Cell2location: a new tool that integrates single cell + spatial transcriptomics data to map tissue atlases at scale. Also new biology in brain/lymph node. Fantastic collab with @OliverStegle, lead by @vitaliikl biorxiv.org/content/10.110…
(thread) Single cell + spatial RNAseq is highly scalable for cell atlassing. However, complex tissues present big challenges for computational methods: need to accurately map dozens of cell types including rare & fine subtypes + account for tech differences between sc/spatial data