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if you're playing it via perps, typically these pairs against majors outperform when alts have been beaten down significantly (trending hard in one direction), and they find a bottom while majors are still ranging
https://twitter.com/blknoiz06/status/1344690086743601154

will be updating this thread on solana all the way to previous all-time highs ($260) - breakout of ~9 month range over ~$25-26 area indicative of positive shift in trend here
https://twitter.com/blknoiz06/status/1357016719492083712generally, you want to be positioned in altcoins when you believe they will outperform bitcoin & rotate back into bitcoin afterwards