We're empowering microbiology labs to prevent and treat infections with DNA sequencing.
Jan 10, 2023 • 8 tweets • 3 min read
BugSeq participated in an independent, peer-reviewed evaluation of tools for taxonomic
classification and profiling of long-read shotgun metagenomic sequencing data: doi.org/10.1186/s12859…. 🧵1/8
“Overall, we find that BugSeq, MEGAN-LR-prot, and MEGAN-LR-nuc provide the best tradeoffs
for all long-read metagenomics data.” 2/8
Feb 22, 2022 • 7 tweets • 4 min read
Need to identify and analyze each organism in a sample (isolate or polymicrobial)? We built a highly-accurate method to tease apart the organisms in a #metagenomic assembly, enabling organism-specific AMR, abundance estimation, strain-typing & more: doi.org/hhqr 🧵1/7
We show that aligning contigs against a nucleotide reference database enables far more precise classification of assembled sequences, surpassing amino acid alignments. 2/7
