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Sarah Jorgensen 🎶🎭🍁 Profile picture
Sarah Jorgensen 🎶🎭🍁
@canuckIDpharm
Perinatal epidemiologist @MCResearchInst | maternal-infant health, vaccine safety, antibiotic stewardship | pharmacist once upon a time
Mar 20, 2021 • 25 tweets • 14 min read
Our #vancomycin AUC-based therapeutic drug monitoring (TDM) counterpoint is out!

Thrilled to work on this with @wfwrighID @BradSpellberg & Twitterless Andrew Shorr 😀

Check out 🧵for highlights? 👇 1/n Brief background.
1st 2009 #vancomycin guidelines recommended troughs 15-20 for serious MRSA infections due to #vancomycin ‘MIC creep’ & associated treatment failures.
But not based on evidence for efficacy or safety 😶

academic.oup.com/ajhp/article-a… 2/n