Sarah Jorgensen 🎶🎭 Profile picture
Postdoc & pharmacist | Research → perinatal epidemiology & infectious diseases
Mar 20, 2021 25 tweets 14 min read
Our #vancomycin AUC-based therapeutic drug monitoring (TDM) counterpoint is out!

Thrilled to work on this with @wfwrighID @BradSpellberg & Twitterless Andrew Shorr 😀

Check out 🧵for highlights? 👇 1/n Brief background.
1st 2009 #vancomycin guidelines recommended troughs 15-20 for serious MRSA infections due to #vancomycin ‘MIC creep’ & associated treatment failures.
But not based on evidence for efficacy or safety 😶

academic.oup.com/ajhp/article-a… 2/n