Dr. Deepti Gurdasani Profile picture
Clinical epidemiology, machine learning, global health. Intersectional feminist. she/her. Won't tolerate bullying, racism or misogyny. All views mine
LittleGravitas 🇺🇦 🌻 🇪🇺 💙 #FBPE Profile picture Dame Chris🌟🇺🇦😷 #RejoinEU #FBPE #GTTO🔶️ Profile picture sl-xf Profile picture John Saunders Profile picture B. S. Profile picture 103 added to My Authors
May 20 12 tweets 3 min read
Just find it truly bizarre that the @UKHSA hepatitis report that came out yesterday, while dedicating pages & pages to different ways to detect Adv has no mention of the results of the two most clinically important investigations:
-liver histopathology
-COVID-19 serology🧵 The report not only shows such low Adv virus loads so as to not even allowing sequencing, but also that among the 68% who did have Adv in blood, it wan't even necessarily the same type. Of those typed (only 35), 77% were 41F, & others presumably other types. US data similar.
May 20 20 tweets 4 min read
Have to say, I'm quite astonished having watched the recent CDC presentations on fulminant hepatitis in children. So much discussed on Adv, with a passing mention of COVID serology (not yet done). Not a single biopsy with Adv in the liver- yet children treated with antivirals.🧵 I'm a trained clinician and epidemiologist. During my clinical training, I'd have had to rigorously justify why I did any test (to avoid incidental positives), why I made a specific diagnosis on a patient, and why I treated for it. I can't really fathom what's happening here.
May 17 4 tweets 1 min read
Hearing from many parents struggling to access vaccination for their 5-11 yr olds. You can book appointments online for all 5+ through the online booking website- this will also tell you about walk-in centres near you (accessible with or without appts)
nhs.uk/conditions/cor… Note: If your child belongs to a high risk group and the gap between doses is 8 wks for them (and not 12 wks), you may not be able to book with this gap using the website, but you can still drop-in to walk-in centres, with the letter showing that your child is eligible for this.
May 17 7 tweets 2 min read
We were sold removal of mitigations as vital to protect economy- now, when the Bank of England is sounding the alarm about poor recovery of the labour market due to long COVID/continuing shielding by those at risk, it's clear there was never a dichotomy between health & economy. It's worth watching the clip- the Governor of the Bank of England actually states that this wasn't even seen after the deep 2008 recession. That this slow recovery of the labour market is worrying, and possibly represents long term impact of the pandemic

parliamentlive.tv/Event/Index/eb…
May 14 22 tweets 6 min read
First bit of analysis from the CDC on hepatitis cases out yesterday. Summary:
-232 cases <=16 yrs
-76% are <5 yrs
-15% admitted to ICU, 6% transplanted, 1 death
-60% adv positive
-74% SARS-CoV-2 positive on serology with 12% PCR +ve
🧵 Epidemiology of these cases- the vast majority have been identified this year, with numbers increasing from week 9 onwards. Cases were sporadically seen before this but appear to have been much rarer.
May 13 27 tweets 8 min read
Several people have reached out to me with this problematic article in the Guardian. Having read it, I think it needs a thorough rebuttal. So here goes. 🧵
theguardian.com/commentisfree/… First, I agree with the author that the impact of omicron has been devastating- in terms of the numbers infected, the substantial increases in long COVID toll in the UK, and >18,600 deaths just this year (yes, deaths with COVID on the death certificate before anyone asks) Image
May 11 5 tweets 1 min read
A question for those of you who're black/brown/marginalised/have faced adversity - given your different perspective on the world - how do you deal with feeling isolated/'outside' because of your diff experience/worldview - which would take immense labour to convey to anyone else? I really struggle with this- often find myself in discussions where I feel like an outsider. These often seem irrelevant/abstract/philosophical to me. I find I can't contribute because they seem trivial to me - and out of touch with at least my view of reality.
May 10 25 tweets 5 min read
A thread on both-siding, tone policing, 'civility arguments'- how they play an important role in strangling challenge & maintaining the status quo. This has been important i maintaining race, gender inequity & maintaining misinformation through the pandemic.🧵 Over the past two years, my overwhelming experience with social media has been attacks against myself and others by 'colleagues'. Some have been completely unprovoked, and others have followed colleagues being challenged on information they have put out by myself or others.
May 8 5 tweets 1 min read
Isn't that the point, though- that the case-hospitalisation rate in children was *the same* for the 1st and 2nd infection in this group of children with re-infection. Re-infection was not 'milder' than the first infection with respect to hospitalisations, contrary to expectation. In the last few months, we've learned that children get re-infected, with early re-infections (<90 days) making up a significant proportion of these. If re-infections are associated with a similar case hospitalisation ratio as 1st infections, surely that's concerning, isn't it?
May 6 19 tweets 6 min read
UKHSA 2nd report on hepatitis out. US reporting 100 cases with 5 deaths so far: TLDR-
for the UK
- 163 cases so far
-91/126 had adenovirus in blood (but *none* in hepatocytes on liver biopsy)
-low viral load
-18% of cases SARS-CoV-2 positive
-no covid serology results yet A lot to unpick but let's start with the UKHSA's stated leading hypothesis- adenovirus. But before we get to that, am really glad to see that they've finally included post-COVID syndrome in their hypothesis (given reports from Israel & Austria, it's important to consider this)
May 6 29 tweets 5 min read
A thread about how privilege shapes individual response to threats - with denial among the privileged impacting the less privileged. I think perhaps how you respond to threats around you has a lot to do with your life experience, sense of security & appetite for reality🧵 Over the past year I've realised that many people around me live in a bubble- it's a comfortable bubble where bad things happen, but there are generally happy endings. And things end up okay overall - maybe there are periods of adversity, but they're overcome in the end.
May 6 5 tweets 2 min read
Actually, I do know it's lower compared to *need*, because the data actually *show this* with ~40% waiting >14 wks for 1st assessment- which you would know had you actually listened before judging. Or literally spoken to the patient community. I *always* evidence what I say. You had me blocked for so long - why did you unblock me? Why? If you don't really want to listen to the information I'm putting out, and want to judge it on your own terms - just block me. It's easier for both of us.
May 6 11 tweets 3 min read
New ONS long COVID report out:
-1.8 million people estimated to have long COVID (28 days)
-1.3 million estimated with impact on day-to-day activity
-791,000 with symptoms for *more than 1 yr*
-the numbers during the omicron wave are 438,000 (equal to the numbers from delta now)🧵 These are data for up to 3rd April (so for infections up to beginning of March) - so impact of BA.2 wave not fully felt yet. The report suggests 1 in 36 people in the community are living with long COVID (28 days) and 1 in 82 (for 1 yr or more).
May 6 13 tweets 3 min read
An extremely privileged take from someone who clearly hasn't interacted with the patient community at all. There are *huge* barriers to care at the moment. And not everyone will even seek care due to the prevalent narrative minimising long COVID. 🧵 These estimates are based on ONS random sampling at population level- 780,000 people estimated to have symptoms for more than a year. You think they're exaggerating too? Public messaging has always minimised the impact of this. Pathways to care are not well known.
May 5 21 tweets 6 min read
This wasn't on my bingo card for the pandemic -
a virus subtype never known to cause fulminant hepatitis -especially not in healthy kids - being implicated among children who're *negative* for this on liver biopsy - but are being treated for this! How did this happen?🧵 There is not a single liver biopsy/explanted liver that we know of that's shown adenovirus yet- but this is the UKHSA's leading hypothesis. And the CDC report shows children being treated with antivirals despite being negative for Adv on biopsy.
cdc.gov/mmwr/volumes/7…
Apr 30 5 tweets 2 min read
Just want to give people an insight what one day in my life is like. A few days ago I was attacked by an epidemiologist who suggested that I was misleading people & spreading misinformation. I engaged with her & explained that she'd misunderstood some basic concepts. 🧵 She continued to troll me, and incited a pile on on me, suggesting that I had cropped screenshots to mislead people. Turned out she didn't understand the basic difference between point prevalence and seroprevalence.
Apr 30 7 tweets 2 min read
I don't say this often enough, but have been thinking of this a lot lately. I'm so grateful for the support here. I don't want to call it support from 'followers', because I've had the privilege to form relationships with so many of you & get to know you & learn from you 🧵 Anyone following my time on social media will know that I get attacked on a daily basis. Most often by 'colleagues'- some new, some that I've challenged on dubious claims in the past. Being an outspoken woman challenging misinformation is unforgiving & leads to unrelenting abuse.
Apr 29 6 tweets 2 min read
You don't seem to understand the difference between point prevalence & cumulative prevalence.... A point prevalence of 17% is 2-3x higher than the *point* prevalence in Mar-Apr. Yes, *cumulative* prevalence is much higher, because it's *cumulative* - but that's not the point! 🤦‍♀️ I know it's popular to attack me for absolutely no reason even if you're wrong, but at least find something you can defend. Is epidemiology really your expertise?
Apr 28 4 tweets 2 min read
So tired of this - the UKSA report actually says that SARS-CoV-2 was found at a 2-3x higher rate in those admitted than in the community, so this is incorrect. Please correct it @CNN

edition.cnn.com/2022/04/27/hea… ImageImage A 17% rate of SARS-CoV-2 positivity isn't expected by any stretch of the imagination - you can check the ONS data on this as well, that shows the same. Also disappointed to see that the post-covid syndrome hypothesis which is a key one, isn't included in the discussion.
Apr 27 4 tweets 2 min read
He acted unlawfully - his policies led to people in care homes dying, and *this* is all he has to say?

A whistleblower said PHE leadership warned the Dept of health about the dangers, but they leaned on PHE to water down their guidelines - causing deaths. From @NafeezAhmed in the @BylineTimes

bylinetimes.com/2021/06/09/hea…
Apr 26 24 tweets 7 min read
Just a bit of reflection on the reporting of fulminant hepatitis in the UK- both in the media, and the recent UKHSA report. I think we need a critical analysis of some of the rhetoric that has been floated around this. Some of the reporting on this seems quite biased. 🧵 First, we don't know what's causing this yet- several hypotheses have been floated, including adenovirus, SARS-CoV-2 co-infection and post COVID-19 syndromes. Here from the UKHSA report yesterday: