Interventional Cardiologist | Medical Education | #cardioEd | Heart Health Awareness | Public health & Patient Education | Let's Beat Heart Disease!
Aug 31 • 9 tweets • 6 min read
Many people believe statins are a product of marketing.
In reality - its neither a miracle, nor marketing, its "medicine."
here is a detailed explanation for people who are miisinformed, a good read for doctors who havent properly read the studies.
read on⤵️
1️⃣ Not all statin trials are the same
The tweet lumps together very different studies.
REVERSAL enrolled just 502 patients with coronary artery disease and measured change in atheroma volume by intravascular ultrasound.
This was a mechanistic study with a morphological end‑point, not a huge trial with multiple chances to “spin” results.
KEY MESSAGE:
Among patients with symptomatic CAD and elevated LDL, use of an aggressive lipid-lowering strategy through treatment with 80 mg atorvastatin was associated with a reduction in the primary endpoint of percent change in atheroma volume compared with a more moderate lipid-lowering strategy through treatment with 40 mg pravastatin. acc.org/Latest-in-Card…
Sep 15, 2024 • 39 tweets • 9 min read
As far as heart disease and it’s risk factors are concerned, NOTHING has sparked as much debate and research as the role of saturated fats.
Does saturated fat increase heart disease?
Or
Does it fix everything like low-carbers say
Let's dive in. A 🧵
(A longish thread - but bear with me on this - this will answer all the questions you have regarding saturated fat and heart health)
The story begins in the mid-20th century when coronary heart disease (CHD) rates skyrocketed. Researchers in Oxford documented a 70-fold increase in coronary deaths over just 35 years.
This alarming trend set the scientific community on a quest to uncover the culprit for coronary artery disease.
Aug 25, 2024 • 9 tweets • 2 min read
You have a silent killer in your bloodstream.
No! It’s not LDL cholesterol. But, it's just as deadly.
What is lipoprotein-a and what should you care? A 🧵
(It’s quite possible that you might have never heard of it!)
🚨 Bookmark this thread to learn how to protect yourself and your loved ones from high Lp-a.
1. What is lipoprotein(a)?
Lipoprotein(a) is a unique particle in blood. It consists of an LDL-like core and apolipoprotein(a) protein. Unlike other lipoproteins, its levels are genetically determined. It promotes atherosclerosis and thrombosis, increasing cardiovascular risk independently of other factors.
Mar 31, 2024 • 15 tweets • 5 min read
What are Triglycerides & Why Should You Care?
Triglycerides are a type of fat found in the blood, which serve as a major source of energy for the body.
They are important because they provide the energy needed for various bodily functions & are stored in fat cells for later use
What happens when you have ⬆️ Triglycerides?
High levels of triglycerides in the blood can be a risk factor for Coronary Artery Disease (CAD) and heart attack, as they are associated with atherogenic lipoproteins that contribute to the development of atherosclerosis.