Dr Sumit Sharma Profile picture
MD | Precision reversal of metabolic dysfunction for high-performers who've tried the basics. Uncovering what others miss. Longevity optimization. London-based.
Apr 4 20 tweets 3 min read
The #1 question in my clinic right now:

“Why is my fasting insulin HIGH...even after 12 hours of not eating?”

Your doctor probably ignored it.

Here’s what’s actually happening: Image Your lab says fasting insulin is “normal” up to 25 µIU/mL.

That’s not normal.
That’s average.

And average = metabolically sick population.
Apr 3 21 tweets 3 min read
Most of my patients weren’t being damaged by high blood sugar.

They were being slowly destroyed by the hormone that rises years before it.

INSULIN

Here are 10 ways chronically high insulin is silently wrecking your body: Image Your doctor checks your glucose.
Not insulin.

That’s the problem.

Because insulin rises years, even decades, before blood sugar.

By the time HbA1c flags... the damage is already done.
Apr 1 24 tweets 3 min read
I’m watching the fasting craze make people sicker than before.

Not because fasting is wrong.

Because people turned a tool into a lifestyle.

Here’s what’s actually happening: Image Fasting isn’t magic.

When you skip meals repeatedly, your body doesn’t just burn fat.

It also breaks down muscle.
Mar 30 23 tweets 3 min read
Most patients are confused: “Should I eat fruit... or avoid it for insulin resistance?”

Some are told: → “Eat more fruit”
Others hear: → “Cut it completely”

Both are wrong.

Here’s the truth about fruit no one tells you (backed by science): Image First, what is insulin resistance?

When you eat → insulin moves glucose into cells.

Insulin resistance = cells stop responding.

So your body produces more insulin.
Mar 29 20 tweets 3 min read
Patients who transform their health, both mentally and physically, share 5 traits.

Not genetics.
Not willpower.

Habits that change biology.

Here’s what they do differently: Image Most people separate:

→ mental health
→ metabolic health

Therapy for the mind. Diets for the body.

That’s the mistake.
Mar 26 21 tweets 3 min read
Everyone calls themselves a metabolism GURU. Coaches. Specialists. Influencers.

I’ve worked with hundreds of metabolic patients over 21 years. Let me save you hours of noise.

Here’s metabolism explained in a 5-minute read & how to improve yours using real science: Image Most people think metabolism = how fast you burn calories.

That’s not metabolism.

That’s one output of metabolism.
Mar 25 22 tweets 3 min read
Growing up in India, alcohol was reserved for weddings and rare celebrations.

Now it’s consumed daily. Normalised. Celebrated.
This legal poison is quietly destroying: • Gut health • Metabolic health • Mental health

Here’s the biology nobody is telling you: Image A generation ago, alcohol had boundaries:

Occasional. Contextual. Celebratory.

That boundary has collapsed.

Stress culture. Socialising. Westernisation.
Mar 22 18 tweets 3 min read
Most people snacking on nuts are grabbing the wrong ones.

The right nuts don’t just curb hunger, they directly reduce visceral fat and improve insulin sensitivity.

Here’s the science-backed list:
(Save this before your next grocery run): Image Visceral fat = fat wrapped around your organs.

Not the fat you can pinch.

The fat you can’t see.
Mar 21 24 tweets 4 min read
One of the most consistent patterns I see in clinic:

Patients with insulin resistance almost always have poor gut health.

That’s not a coincidence.

That’s biology: Image Your gut lining is one cell thick.

One layer separates your bloodstream from trillions of bacteria and undigested food.

When that barrier breaks down, intestinal permeability - bacterial fragments called LPS (lipopolysaccharides) enter your bloodstream.
Mar 20 25 tweets 4 min read
After working with hundreds of patients with insulin resistance, the most common snack I see quietly damaging metabolic health the most isn’t cake or fizzy drinks.

It’s BISCUITS.

Eaten daily. With tea. Feeling harmless.
Here’s why they’re quietly driving insulin resistance: Image First, what is insulin resistance?

Your cells stop responding properly to insulin — the hormone that moves glucose from your blood into your cells for energy.

Your pancreas compensates by producing more insulin.
Mar 18 21 tweets 3 min read
I've reviewed hundreds of patient cases where: • diet was perfect • exercise was consistent

But metabolic markers stayed broken.

The missing variable: DEEP SLEEP.

Here’s why it’s non-negotiable for metabolic health: Image Most people think sleep is rest.

It’s not.

Deep sleep (slow-wave sleep) is your body’s metabolic repair window.
Mar 17 19 tweets 3 min read
Your fasting glucose is 88 mg/dL. “Perfectly normal,” your doctor says.

But your HbA1c just came back at 6.1% - Prediabetic.

How can both be true at the same time?

This paradox is more common and more dangerous than people realise: Image First, understand what these tests actually measure.

Fasting glucose = a single snapshot.

Your blood sugar at one moment in time after 8+ hours without food.
Mar 12 19 tweets 3 min read
The most common thing I hear from patients over 40 with: • Fatty liver • Type 2 diabetes • High blood pressure

“No one told me I could reverse this.”

You can, and it's simple.

Let me share 10 easy steps that can transform your well-being: Image After 21 years in medicine and working with hundreds of metabolic patients, I can tell you:

These 3 conditions rarely arrive alone.

They share ONE root cause.

Insulin resistance.
Mar 10 17 tweets 3 min read
After reversing insulin resistance in hundreds of patients, The #1 movement habit that separates those who reverse it... from those who don’t?

It’s not 10,000 steps. It’s when you walk.

Here’s why a 10-minute post-meal walk outperforms an hour of daily movement: Image Most people treat movement like a bank account.

Deposit 10,000 steps anywhere.

Balance looks good. Job done.

But your metabolism doesn’t work on daily averages.
Mar 9 17 tweets 3 min read
Most fatigue, high blood pressure, and insulin resistance cases I see have one overlooked factor in common.

It's not stress. Not poor sleep. Not even diet.

It's a mineral deficiency your standard blood test almost always misses. Let's talk about potassium: Image “Your potassium is normal.” That’s what you’re told.

Here’s what most doctors don’t explain: Serum potassium measures ~2% of your total body potassium.

The other 98% lives inside your cells.

That’s where the deficiency hides.
Mar 4 17 tweets 3 min read
After reversing insulin resistance in hundreds of patients, I found one dietary change that moves the needle faster than anything else.

It’s what you eat for breakfast.

Here’s why breakfast is your most powerful metabolic lever: Image Most people with insulin resistance eat the worst possible breakfast:

Toast.
Cereal.
Granola.
Orange juice
“Healthy” smoothies.
Mar 3 23 tweets 3 min read
Most high performers make reversing insulin resistance 10x harder than it needs to be.

I’ve watched brilliant people fail at this.

Not from lack of effort. From too much of it.

Here's how: Image I’m Dr Sumit Sharma. 21 years in medicine. I run a precision metabolic clinic.

Complexity keeps smart people metabolically stuck & the exact 3-lever sequence I use in every 90-day reversal.

Save this. It replaces 6 months of trial and error.
Mar 2 19 tweets 3 min read
I’ve seen hundreds of “normal BMI” professionals blindsided by a condition their doctor never mentioned.

It’s called SARCOPENIC OBESITY.

And it may be the most underdiagnosed metabolic crisis of our time: Image Sarcopenic obesity =

Losing muscle WHILE gaining fat
At the same time.

Even at a “healthy” weight. The scale doesn’t move.

Your metabolism quietly collapses.
Mar 1 22 tweets 3 min read
The #1 thing destroying high performers’ energy, focus, and body composition:

INSULIN.

It either makes or breaks your metabolism.

This 5-minute read could save you years of metabolic decline: Image I’m Dr Sumit Sharma.

21 years in medicine.

Now running a precision metabolic health program.

After working with hundreds of insulin-resistant patients, one truth is clear: Insulin runs the show.
Feb 28 19 tweets 3 min read
Your doctor spends 4 minutes reviewing your cholesterol. LDL is “high.”A statin is prescribed.

20 years of medication...for a problem that might respond to 90 days of metabolic repair.

Here’s what that 4-minute review often misses: Image After 21 years in medicine and treating thousands with insulin resistance, I can tell you: LDL alone rarely tells the full story.

Here’s what actually determines risk:
→ When statins are essential
→ When lifestyle should come first
→ The 4 markers that truly predict cardiac events
Feb 26 26 tweets 3 min read
I’ve reviewed hundreds of blood panels where the doctor said:

“Your liver’s fine.” It wasn’t.

Your liver is where metabolic disease starts.

Here’s how to know whether yours is burning fat or storing it: Image I’m Dr Sumit Sharma. 21 years in medicine.
Now focused purely on metabolic health.

By the end of this thread you’ll know:
• The “normal” ranges that aren’t optimal
• The 4 markers that reveal your liver’s true state
• The 90-day protocol I use to shift livers from storage mode to burn mode