"US Government researchers in 1950s were infecting monkeys with smallpox
Monkeypox was first seen in 1958, in monkeys used in medical experiments
first recorded human case occurred during a smallpox vaccination drive in Congo in 1970"
"It (cidofovir) has inhibitory effects on varicella-zoster virus replication in vitro although no clinical trials have been done to date, likely due to the abundance of safer alternatives such as aciclovir"
May 19, 2022 • 4 tweets • 2 min read
U.S. MAY BE BARRELING TOWARD RECESSION IN NEXT YEAR
"western block is going to have 2009 like situation in near future.
great economical recession is impending, following ukr-russ war.
india will suffer least, west to go into great depression"
#akcgenomics
TELOMERE SHORTENING
AND PREVENTING AGING BY CHEMICAL MEANS
"Berberine Inhibits Telomerase Activity and Induces Cell Cycle Arrest and Telomere Erosion in Colorectal Cancer Cell Line, HCT 116" @drakchaurasia@Parsifaler mdpi.com/1420-3049/26/2…
BERBERINE
Lewis rats were immunized with porcine cardiac myosin to induce experimental AUTOIMMUNE MYOCARDITIS,TREATED WITH BERBERIN nd specific JAK inhibitor
BERBERIN and AG490 significantly reduced impaired cardiac function and pathophysiological severity
#akcomicron
OMICRON-- DIFFERENT MODE OF CELL ENTRY
more cell types infected
"uses an endosomal pathway for entry that increases number of cell types it can infect. This switch of entry pathway could explain increase in transmissibility of Omicron variant" news-medical.net/news/20220109/…
DRUGS BLOCKING ENDOCYTOSIS
omicron variants
COMMON ANTI-PARASITIC AGENT EASES MOTOR SYMPTOMS, AIDS REMYELINATION IN MS MOUSE MODEL
IVM in autoimmune disease
"ivermectin eased clinical manifestations of experimental autoimmun encephalomyelitis (EAE;an induced autoimmune disease similar to MS in human multiplesclerosisnewstoday.com/2018/07/13/ant…
Jul 6, 2021 • 7 tweets • 3 min read
LAMBDA VARIANT
"According to Public Health England (PHE),information about Lambda Variant Covid Symptoms is given below.According to PHE,no patient of this variant has had fatal disease so far.PHE reports that lambda version causes any major ill-effects" mpnrc.org/lambda-variant…
*drugs are working good in new strains too, but virus is looking slightly faster than drugs
*usual one drug regime used in older strain, getting insufficient, specially in younger population
1/1@Psychoman53 1/2
*in youngsters, increased dosage/number of drugs, are needed to control progression of disease, and still more aggressive efforts are needed to combate hypoxia
