Daniel George Profile picture
Cleveland native, living in Appalachia & working at Penn St College of Medicine. Tweets are my own.
Dec 21, 2021 11 tweets 6 min read
I've joined colleagues petitioning the FDA to withdraw Biogen's license for aducanumab, a drug that hasn't demonstrated benefit to patients & poses major safety issues (brain bleeds/swelling). Besides being case of regulatory capture, Biogen's marketing has been deeply cynical... After receiving startling approval last June (again, for a drug that doesn't appear to work & has already been linked to deaths), Biogen set the price at $56k annually, despite initial projections of $3k-$8k. This doesn't even factor in cost of PET scans, clinical infusion, etc.
Nov 11, 2020 15 tweets 5 min read
A research team I’m part of just published data looking at the ‘diseases of despair’ crisis over the last decade (full article is free and available online). A brief summary of our findings below, and some thoughts.... bmjopen.bmj.com/content/10/10/… Diseases of despair are the *clinical* manifestations of substance abuse, suicidal thoughts/behaviors & alcohol dependency that precede despair-related *deaths* that have been in the news in recent years ImageImage