Biologists love balancing selection, but detecting it is hard! Luckily, many new methods to detect signatures of balancing selection from population-level genomic data have been developed recently, and we have a deep overview of those methods for you! 🧵
academic.oup.com/gbe/article/15… Before diving deep into recent methods, we provide the historical relevance of balancing selection throughout the 20th century

Our paper "Polygenic Scores for Height in Admixed Populations" is out on G3! @GeneticsGSA Why don't polygenic risk scores predict height accurately if ancestry of test cohort is not European? It's complicated! 1/n g3journal.org/content/early/… One barrier to the use of PRS in clinical practice is that the majority of GWAS come from cohorts of European ancestry, and predictive power is lower in non-European ancestry cohorts. There are many possible reasons for this decrease 2/n