Academic rheumatologist in Leeds. Interested in lupus, prevention, skin and joint involvement, clinical trials and stratification. Jokes aren’t my own.
Jul 27, 2018 • 12 tweets • 8 min read
@BeckySueToo@RheumJC Let me explain...
@BeckySueToo@RheumJC What is wrong here is using total B cells. There are sunsets of CD19. Broadly speaking: naive (have not received Ag stimulation, not activated and no T cell help); memory (antigen experiences, been in a terminal centre) and plasmablast (trying to become a plasma cell)...