I’m a big fan of Milk Thistle as a mast cell stabilizer. Milk Thistle contains Silibinin.

“Silibinin reduces the production and mRNA expression of pro-inflammatory cytokines such as TNF-α, IL-6, and IL-8, suggesting that silibinin could be used for the treatment of mast cell-derived allergic inflammatory diseases.” ncbi.nlm.nih.gov/pmc/articles/P…

I’m noticing women are getting long covid more often but men seem to be suffering strokes post covid more often. Just from observing people I know, reality tv, anecdotally. My fiancé works in neurology and it’s just constant strokes and brain tumours now. So scary. This is the new normal everyone wanted so bad. Constant illness and disability. A healthy society is a thing of the past. I hope you are all happy with your decision to let a BSL-3 pathogen rip. Condemning everyone to an early grave with lots of suffering along the way.

Seeing way too many people posting about bleeding from the eyes on Reddit for H5N1 to not be spreading H2H. I don’t think it’s going to be as fatal though in mammals as it is in avian species. I’m seeing the same pattern and signs as I did in November 2019 that led me to believe there was going to be a pandemic. I told all my friends to start masking in December 2019.

It’s hard for me to share these photos but I want people to see what this virus can do. These photos are from 2022.

I have been bald since May 2022 when my hair started to fall out after my first Covid infection which was ASYMPTOMATIC. I was diagnosed with alopecia areata, which is an autoimmune response. I lost my hair, brows and lashes. I also had vascular lesions everywhere. I also developed solar urticaria, meaning I’m allergic to UVA/UVB. Indoor lights burned my skin. The sun gave me anaphylaxis. I have not been able to be in direct sunlight in over 2 years. My eyes swelled shut for several weeks.


I can go outside in the shade now at least if the UV is low enough. My hair is starting to grow back for the first time normally. My eyelashes and eyebrows fully grew back. These are all wigs

About to have a video conference with specialists about my lymphocyte panel results. Okay so they confirmed I have long covid viral persistence in my monocytes. Dr. Patterson prescribed HIV antivirals and a statin. The statin can get the spike protein out of the body via apoptosis. I am going to be doing 6 months of Maraviroc and Atorvastatin. Confirms I have vascular inflammation and damaged endothelial cells. He said the spike can persist forever if you don’t clear it. He also said it was not LIVE viral replication. It’s the viral fragments left behind after an infection that cause a cytokine storm.

Sounds mild, right?

My current updated protocol for managing long covid, ME/CFS, MCAS, POTS, Fibromyalgia.

Taurine (powder form 1.5g scoop x2)
Berberine (500mg x2)
Probiotics - lactobacillus plantarum
Arginine (protein powder form 5g scoop)
Glycine (5,000-10,000mg)
Lysine
Collagen Peptides
Magnesium Bisglycinate
Resveratrol (1200mg a day)
High dose vitamin c (1000mg)
Vitamin B2, Liquid B12, K2, B3
High dose vitamin D3 (5,000-10,000ui)
Omega-3
NAC (500mg x 2)
D-Alpha Lipoic Acid w biotin

Mast cell stabilizers:
Pycnogenol (French maritime tree bark) (250 mg)
Quercetin (1000mg)
Spirulina
Stinging Nettle
Olive Leaf Extract
Sweet fennel, milk thistle
Turmeric
Antihistamines: loratadine 10mg x2 (am), famotidine 20mg x2 , hydroxyzine 25mg (pm)
Activated charcoal (as needed to bind mycotoxins & heavy metals)

Propranolol (for POTS)

Gabapentin (200mg x2 for SFN)
Cooper, Zinc, Selenium
Melatonin
21mg nicotine patches worn continuously

I use betadine nasal sprays, CPC mouthwash.

I also do a low histamine diet, no soy, no gluten, low carb, high protein. This protocol I put together helped me go from severe to mild and gave me quality of life back.

https://x.com/erincandy/status/1801245274787946624?s=46&t=67VdfUG2WKw_-l_qm47YLg

I feel so motivated today I’ve already read 14 medical journals. I’m now convinced nicotine helps LC not only because of the theory that it might dislodge viral fragments from acetylcholine receptors, I think it’s also a mast cell stabilizer that can cross the BBB. Everything always comes back to mast cell activation. That is the key to solving LC and ME/CFS

Managing MCAS is a 24/7 job but I’ve got it controlled now that all my LC symptoms are gone and my other autoimmune diseases seem to be in remission. Not getting PEM, usual fibromyalgia pain is gone, my hair is growing, my blood circulation is better. I’m still allergic to UV but it’s slowly getting less severe the longer my mast cells are stable.

I’m doing research now to see if there’s a connection with nicotine and mast cells because my recovery since adding it has pushed me from severe to mild. So far I’ve found that nicotine agonists inhibit histamine release from human basophils so I think nicotine might be a mast cell modulator. “Inflammatory substances released by mast cells induce and maintain the allergic response. The mast cells degranulate rapidly (in seconds) releasing the preformed chemical mediators, including histamine and β-hexosaminidase that play a critical role in the immediate-type allergic response.”

In this study they found that stimulation of FcεRI IgE receptors caused rapid mast cell degranulation (which causes MCAS symptoms). They compared the effects of cromoglycate sodium (a well known mast cell stabilizer) and Nicotine on mast cells.

Cromo Sodium inhibited the FcεRI response by 10-15%. In comparison a low dose of Nicotine inhibited the response by 40-60%! Nicotine is relatively a strong inhibitor of mast cell cytokine production. However because nicotine has such a short half life this study shows that continuous dosing of nicotine is needed to suppress the late stage mast cell degranulation by inhibiting the release of certain inflammatory cytokines.

There are nicotinic acetylcholine receptors on mast cells.

“property of the nAChRs on mast cells might be accessible to novel therapeutic approaches to control allergic diseases and allergic asthma”

Severe MCAS was driving all of my symptoms and since adding nicotine patches, I can’t believe the quality of life I’ve recovered in such a short time.

I focused on calming TLR4 to stop the cytokine storm that was causing systemic inflammation using senolytic drugs. Huge part of my recovery

https://twitter.com/doc4care/status/1802025872800493943

Metformin worked the best

https://x.com/erincandy/status/1756724398185124198?s=46&t=67VdfUG2WKw_-l_qm47YLg

I’ve recovered from long covid twice before and I’m finally recovering again. Things that have been most helpful towards recovery: amino acids, collagen peptides, metformin, antioxidants & nicotine patches. Also supplements with antiviral effect, calming TLR4, treating MCAS. I’m sleeping 7-8 hours a night and my anxiety is gone. Orthostatic intolerance improved. Pain improving. Inflammation battle won. This is a good article on natural antivirals, something to research if you were denied paxlovid bc of eugenics like I was:

Antiviral foods in the battle against viral infections: Understanding the molecular mechanism

ncbi.nlm.nih.gov/pmc/articles/P…

Tested my baseline with the nicotine patches and I had a major baseline increase. No longer getting PEM just existing. Only took 5 days on NRT to get a baseline increase. I had to double my patches to 14mg because my body metabolizes drugs too fast, other people will likely need lower dose. This is not medical advice just my experience

Continuing the nicotine patch test experiment with a patch dosage
increase today to see if I can raise my baseline more. I wore no patches yesterday and my baseline was the same with them. Brain fog, orthostatic intolerance and energy all improved. Most of my LC symptoms are gone

Forever in supplemental debt but these are the only things that have given me any sort of quality of life.

Current MCAS arsenal. (Not pictured are RX meds - Metformin, Propranolol, Gabapentin, antihistamines ( h1&h2). The ones that are making the most difference right now that I would say are my must haves are the Glycine, The Stinging nettle and Spirulina have stopped MCAS flares instantly, Olive leaf and quercetin/BBR. I have only been taking the stinging nettle and spiruilna for a week and my mast cells finally feel like they are stabilizing for the first time since I was reinfected with JN1 in February.

Once you realize that aging is a side effect of immune system damage, you realize why anti-aging drugs help with long COVID symptoms.

Taurine deficiency as a driver of aging

“Aging is associated with physiological changes that range in scale from organelles to organ systems, but we are still working to understand the molecular basis for these changes. Studying various animals, Singh et al. found that the amount of the semi-essential amino acid taurine in circulation decreased with age. Supplementation with taurine slowed key markers of aging such as increased DNA damage, telomerase deficiency, impaired mitochondrial function, and cellular senescence. Loss of taurine in humans was associated with aging-related diseases, and concentrations of taurine and its metabolites increased in response to exercise. Taurine supplementation improved life span in mice and health span in monkeys. Mechanistically, taurine reduced cellular senescence, protected against telomerase deficiency, suppressed mitochondrial dysfunction, decreased DNA damage, and attenuated inflammaging. In humans, lower taurine concentrations correlated with several age-related diseases and taurine concentrations increased after acute endurance exercise. Thus, taurine deficiency may be a driver of aging because its reversal increases health span in worms, rodents, and primates and life span in worms and rodents. Clinical trials in humans seem warranted to test whether taurine deficiency might drive aging in humans.

I do my best thinking on edibles. Who’s ready for a new long COVID thread? Let’s learn about immunosenescence - impact of senescent cells and senolytic drugs! I’ve been focusing my latest research on TLR4, cytokine storms, cell apoptosis and the powerhouse of the cell, mitochondria. As we unravel the web of long COVID, recent research suggests that toll like receptor 4, or TLR4, may be the culprit behind the induction of a proinflammatory cytokine expression caused by the SARS-CoV-2 spike protein activating TLR4. Interestingly enough activation of TLR4 by viral glycoproteins has been seen in EBV, RSV and dengue virus.
The theory is that activation of TLR4 is what is driving the aggressive inflammatory response
of uncontrollable release of high levels of proinflammatory cytokines, increased activation of immune cells, and harmful hyperinflammation seen in long COVID. This cytokine storm causes the damage we’re seeing in long COVID.. dysautonomia, organ damage, organ failure and death. By calming over activation of TLR4 with inhibitors, decreased systemic hyperinflammation could help relieve long COVID symptoms.

Most people don’t want to hear that diet is the most important thing in controlling mast cells but it’s true. The gut microbiome is the most important thing in the body after our brain. I tried everything for a year a half and it wasn’t until I completely changed my lifestyle & diet completely with a strict low histamine diet and cut out all my sensitivities, within 3 months MCAS & leaky gut were better and then my long covid symptoms started to drastically improve. I only eat whole grains, no bleached flour or wheat germ, no corn or soy at all, only mozza, cream cheese and yogurt for dairy. My food sensitivities and allergies are improving, I had a cookie yesterday and it didn’t send me into a flare. If you have mast cell issues, you’re gonna wanna learn about histamine in food. At this point I consider myself a mast cell specialist. I know the histamine levels of everything now. You want to stick with foods that are fresh, the fewer ingredients the better. Nothing frozen or processed. You want to stay away from things that are fermented, very high histamine levels. Leftover food in your fridge is going get higher in histamine the longer it’s in there. I Google the histamine levels in everything. Vinegar is your enemy. Probiotics are your friend. I would also do intermittent fasting because your body will have more energy throughout the day when your body isn’t constantly trying to digest food, and you will get more out of the food you eat. I would start here and learn about good histamine foods and bad histamine foods histaminintoleranz.ch/downloads/SIGH…

The 24/7 feeling like you’re gonna die but you don’t long COVID feeling I had since March 2022 is finally gone. The crippling daily fatigue is gone again. I had a remission event Aug/sept but then I crashed in October and was diagnosed with Postural orthostatic tachycardia syndrome in December. Been on beta blockers since Dec 6, my heart is lowering a bit but I need a higher dosage for sure. Still waiting on the results of my Holter monitor. Definitely won’t hear from my cardiologist until the new year. But I feel like my MCAS is stabilized, my mental health is much better since going off my SSRI and SNRI actually. I’m not having panic attacks or anxiety. My insomnia is under control again. I’m feeling so much better overall other than my POTS. It’s maddening feeling better from all my other LC symptoms, and feeling normal when I lay down now. But I can’t really walk or do anything other than light activity around the house without my heart rate shooting to 130,140^ and then the POTS symptoms start. My must have supplements for LC:
Probiotics (Lactobacillus plantarum & bifidobacterium)
Quercertin
NAC
B1, B2, B3, B6, B12
Reishi mushroom caps (brain fog gone most days)
Tumeric/Curcumin
Magnesium w electrolytes, Selenium, Copper
Antihistamines: H1 & H2 blockers (Claritin, Benedryl, Pepcid)
Sodium tabs (for POTS)
D3
Omega 3
Resveratrol (antioxidant)
Alpha Lipoic Acid (antioxidant)
Coenzyme Q10

As someone who studied history I think that we are in a period that will be considered the dark ages of public health in future history books. Not only are we actively regressing on public health measures during the worst pandemic in modern times; we are allowing an unprecedented scientific experiment on 8 billion people with a novel coronavirus that is airborne, vascular and the worst virus humanity has faced since the Black Death. And we are failing miserably. We are actively headed for the extinction of humanity if we continue on this trajectory. And the majority of people are in denial because reality is too scary. Guess what, it is fucking scary. People in the category of COVID minimizing or denial (including people who work in public health!) actively become defensive when they see people masking because they are reminded of the reality they actually live in, not the one they want to think still exists. I’m seeing reports
Of schools banning HEPA filters bc it’s scary. Most ppl don’t know COVID is airborne. Most ppl don’t know repeat COVID will slowly kill you. The only way out of this is a GLOBAL public health response of a clean air initiative that cleans all public shared indoor air. There was a time when indoor plumbing was seen as something unattainable for the general public, not a priority, not commonplace in first world countries. We are at a point in time where in the near future clean air acts will be the standard that we can’t live without, and future generations will be wondering what the fuck all you people denying masks and clean air were thinking. Be on the right side of history and mask up and demand clean public indoor air. COVID is airborne. Proper air ventilation in public spaces cut COVID exposure by 89%. Be the change you want to see in the world, wear a mask during COVID surges and demand that schools, hospitals, LTC homes, all public indoor spaces, work places, offices, stop forcing eugenics on everyone and clean the fkn shared air! #COVIDisAirborne #CovidIsNotOver

I have literally soooooooo much evidence from their official telegram that the freedom convoy is a massive front for alt right extremism as a global movement and it all leads back to the trump effect. I mean General Flynn is sending support to the organizers on telegram ffs I really just want this to be exposed before the CPC and PPC become the GQP because that’s where Canada is headed if this isn’t taken seriously for what it is. #OttawaOccupation #CouttsCrisis is Canadas January 6th at the core

So you accidentally participated in domestic terrorism

#OccupyOttawa #Coutts #freedomconvoy #FluTruxKlan 🤦🏼‍♀️ The fringe conspiracy theories are spinning about the gofundme being paused for violating terms and service, and now they’re getting refunds. Of course they think it’s a deep state plot, not because they got brainwashed by antivax propaganda and funded domestic terrorism #cdnpoli

We are all fucked if omicron keeps mutating. Omicron BA2 already has 4/9 of these worst case scenario spike protein mutations. 600 fold increase. It’s not fear mongering it’s realism and this isn’t becoming an endemic with antivaxxers existing. biorxiv.org/content/10.110… These are the most worrying spike protein mutations. Omicron is mutating to survive and infect as many people as possible. Get boosted. Get your love ones boosted. Hope that the omicron specific boosters are ready sooner than later.