Frank Santoriello Profile picture
@CUAnschutz Micro PhD Candidate | Cholera nerd working with @BCID2014 | Artist on the side | IG: @microbialmiscellanea | he/him | Currently postdoc hunting
Feb 5, 2021 9 tweets 2 min read
I’d like to tell you all about the last 3 weeks of my life. I still see/hear takes about how Covid isn’t that dangerous or is only a problem for older people. So I’d like to tell you about my experience as a healthy 30 yo. A thread:

1/9
On Jan 16th (Day 1) my fiancé tested positive for SARS-CoV-2. We spent the next week quarantining from each other and masking in our own home. She had a few days of symptoms and then was mostly fine.

2/9
Dec 9, 2019 21 tweets 5 min read
Okay so now that I have arisen from my post-flight coma, let’s talk about the Vibrio cholerae T6SS. Primarily my favorite effector/immunity module, Aux3. A thread... So the T6SS is essentially a bacterial harpoon gun that looks like a phage. The V. cholerae cell loads it on its membrane to stab and kill neighboring competitors. It does this with toxic proteins called effectors. A cell and its “kin” are immune to their own effectors.
Oct 2, 2019 17 tweets 12 min read
#Inktober2019 Day 1: Ring. Spirosoma linguale is a non-pathogenic microbe that forms beautiful ring-like or horseshoe shaped cells. To me, they resemble microscopic curly fries. #Inktober2019 Day 2: Mindless. Your reminder that the amazing microbial diversity we observe is due to the mindless march of evolution. Evolution has no agenda. It is random variation and fitness-based selection, and microbes are fantastic at developing new ways to be fit.