Our single-nucleus cross-tissue cell atlas is out in @ScienceMagazine as part of @humancellatlas: science.org/doi/10.1126/sc… w/ Eugene Drokhlyansky, @ShankaraKAnand, @EvgenijFiskin, @ayshwaryas, @francoisaguet, @asegre, Orit Rozenblatt-Rosen, @KArdlie, Aviv Regev & many others 1/ Understanding how disease genes function requires analysis of cell profiles from large human cohorts and multiple tissues across the body. Single-nucleus profiling methods enable us to study frozen, banked samples which is a big step toward this goal 2/

We are very excited to share our single-nucleus cross-tissue atlas w/ Eugene Drokhlyansky, @francoisaguet, @ShankaraKAnand, @ayshwaryas, @EvgenijFiskin, @asegre, Orit Rozenblatt-Rosen, @KArdlie, Aviv Regev and many others 1/n We applied four snRNA-seq methods to each of 25 samples from 8 banked GTEx tissues, 16 donors, generating a cross-tissue atlas of 209,126 nuclei profiles
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