Siân Owen Profile picture
Microbiologist. Phage phanatic. Mushroom hunter. Enthusiastic explorer of bacterial genomes. Postdoc in the @baym lab, @harvardmed. Previously @jay_salsa lab.
Jul 14, 2020 19 tweets 8 min read
I'm very excited to finally share the preprint for a project I've been working on for >4 years! Here's a thread with some of the highlights: In a previous study we identified genes that were highly-expressed in Salmonella prophages, and were probably modulating cell biology (more on that here ). One of the genes was the mysterious bstA
Feb 6, 2020 14 tweets 5 min read
Online today in #MGen : How we can use transcriptomic data to reveal new temperate phage biology microbiologyresearch.org/content/journa… This started with a simple idea and became a nice proof of concept. And one of the last papers from my PhD in @jay_salsa lab !
( a thread ⤵️ ) @MicrobioSoc Image Phages can be broadly classified into two groups: temperate and virulent (or lyosogenic and lytic if you prefer). Temperate phages are by far the most interesting of the two! (Sorry phage therapists). This is because: